This gene encodes a serine threonine protein kinase that has similarity to the catalytic subunit of cyclic AMP dependent protein kinases. The encoded protein is developmentally regulated and may be involved in renal epithelial morphogenesis. This protein may also be involved in macrophage and granulocyte maturation. Abnormal recombination between this gene and a related pseudogene on chromosome Y is a frequent cause of sex reversal disorder in XX males and XY females. Pseudogenes of this gene are found on chromosomes X, 15 and Y. [provided by RefSeq, Feb 2010].
Li, Li, Amsler, Hyink, Wilson, Burrow: "PRKX, a phylogenetically and functionally distinct cAMP-dependent protein kinase, activates renal epithelial cell migration and morphogenesis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 14, pp. 9260-5, (2002) (PubMed).
Aliases for PRKX 抗体
protein kinase, X-linked (PRKX) 抗体 protein kinase, X-linked (Prkx) 抗体 Pkare 抗体 PKX1 抗体