THOC7 抗体
(THO Complex 7 (THOC7))
Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO complex (By similarity).
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23 results
THOC7
适用: 人, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Pig, 猴
WB
宿主: 兔
Polyclonal
unconjugated
1 image
THOC7
适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼
WB
宿主: 兔
Polyclonal
unconjugated
1 image
Latest Publications for our THOC7 抗体
: "Human corneal endothelial cells employ phosphorylation of p27(Kip1) at both Ser10 and Thr187 sites for FGF-2-mediated cell proliferation via PI 3-kinase." in: Investigative ophthalmology & visual science, Vol. 52, Issue 11, pp. 8216-23, (2011) (PubMed).: "An ataxia-telangiectasia-mutated (ATM) kinase mediated response to DNA damage down-regulates the mRNA-binding potential of THOC5." in: RNA (New York, N.Y.), Vol. 17, Issue 11, pp. 1957-66, (2011) (PubMed).
: "Nuclear localization of the pre-mRNA associating protein THOC7 depends upon its direct interaction with Fms tyrosine kinase interacting protein (FMIP)." in: FEBS letters, Vol. 583, Issue 1, pp. 13-8, (2008) (PubMed).
: "Recruitment of the human TREX complex to mRNA during splicing." in: Genes & development, Vol. 19, Issue 13, pp. 1512-7, (2005) (PubMed).
Aliases for THOC7 抗体
THO complex 7 (Thoc7) 抗体THO complex 7 (THOC7) 抗体
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