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TCF3 抗体

(Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3))
This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1\;19), with PBX1), childhood leukemia (t(19\;19), with TFPT) and acute leukemia (t(12\;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Sep 2011].
TCF3 抗体  (AA 545-654) TCF3 抗体  (AA 545-654) TCF3 抗体 (AA 545-654) (ABIN563112)

TCF3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5G2 unconjugated

TCF3 抗体  (C-Term) TCF3 抗体  (C-Term) TCF3 抗体 (C-Term) (ABIN657912)

TCF3 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB33747 unconjugated

TCF3 抗体 TCF3 抗体 TCF3 抗体 (ABIN1724729)

TCF3 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 6B8 unconjugated

TCF3 抗体 by Grade

Find TCF3 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

TCF3 抗体 by 适用

Find TCF3 抗体 for a variety of species such as anti-Human TCF3, anti-Mouse TCF3, anti-Rat TCF3. The species listed below are among those available. Click on a link to go to the corresponding products.

TCF3 抗体 by 应用范围

Find TCF3 抗体 validated for a specific application such as WB, ELISA, FACS, IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

TCF3 抗体 by 抗体来源

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TCF3 抗体 by 抗原表位

Find TCF3 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

TCF3 抗体 by 克隆形成能力

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TCF3 抗体 by 克隆

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TCF3 抗体 by 标记

Find TCF3 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular TCF3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (3)
Cat. No. ABIN563112
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS, IHC (p)
Validations
  • (5)
Cat. No. ABIN657912
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS
Validations
  • (2)
  • (2)
Cat. No. ABIN1724729
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (1)
  • (1)
Cat. No. ABIN701605
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7180263
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN190880
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7172509
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7138838
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (1)
Cat. No. ABIN3187205
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Drosophila melanogaster, Guinea Pig, Hamster, Human, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN203333
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Dog, Horse, Human, Monkey, Mouse, Pig, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN202854
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (1)
Cat. No. ABIN5539886
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (2)
Cat. No. ABIN2780485
Quantity 100 μL
Datasheet Datasheet
Reactivity Chicken, Human
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN7297090
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN701607
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our TCF3 抗体

He, Long, Zhong, Fu, Li, Lin: "Sustained endoplasmic reticulum stress inhibits hepatocyte proliferation via downregulation of c-Met expression." in: Molecular and cellular biochemistry, Vol. 389, Issue 1-2, pp. 151-8, (2014) (PubMed).

Schmeisser, Grabrucker, Bockmann, Boeckers: "Synaptic cross-talk between N-methyl-D-aspartate receptors and LAPSER1-beta-catenin at excitatory synapses." in: The Journal of biological chemistry, Vol. 284, Issue 42, pp. 29146-57, (2009) (PubMed).

King, Van der Put, Blomberg, Riley: "Accelerated Notch-dependent degradation of E47 proteins in aged B cell precursors is associated with increased ERK MAPK activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 6, pp. 3521-9, (2007) (PubMed).

Greenbaum, Lazorchak, Zhuang: "Differential functions for the transcription factor E2A in positive and negative gene regulation in pre-B lymphocytes." in: The Journal of biological chemistry, Vol. 279, Issue 43, pp. 45028-35, (2004) (PubMed).

Cole, Zhang, Geyra, Kang, Krauss: "Positive regulation of myogenic bHLH factors and skeletal muscle development by the cell surface receptor CDO." in: Developmental cell, Vol. 7, Issue 6, pp. 843-54, (2004) (PubMed).

Nie, Xu, Vladimirova, Sun: "Notch-induced E2A ubiquitination and degradation are controlled by MAP kinase activities." in: The EMBO journal, Vol. 22, Issue 21, pp. 5780-92, (2003) (PubMed).

Snider, Thirlwell, Miller, Moon, Groudine, Tapscott: "Inhibition of Tcf3 binding by I-mfa domain proteins." in: Molecular and cellular biology, Vol. 21, Issue 5, pp. 1866-73, (2001) (PubMed).

Firulli, Hadzic, McDaid, Firulli: "The basic helix-loop-helix transcription factors dHAND and eHAND exhibit dimerization characteristics that suggest complex regulation of function." in: The Journal of biological chemistry, Vol. 275, Issue 43, pp. 33567-73, (2000) (PubMed).

Bain, Robanus Maandag, te Riele, Feeney, Sheehy, Schlissel, Shinton, Hardy, Murre: "Both E12 and E47 allow commitment to the B cell lineage." in: Immunity, Vol. 6, Issue 2, pp. 145-54, (1997) (PubMed).

Bain, Gruenwald, Murre: "E2A and E2-2 are subunits of B-cell-specific E2-box DNA-binding proteins." in: Molecular and cellular biology, Vol. 13, Issue 6, pp. 3522-9, (1993) (PubMed).

Aliases for TCF3 抗体

transcription factor 3 (TCF3) 抗体
transcription factor 3b (tcf3b) 抗体
transcription factor 3 (Tcf3) 抗体
transcription factor 3 L homeolog (tcf3.L) 抗体
transcription factor E2a (tcfe2a) 抗体
A1 抗体
AA408400 抗体
ALF2 抗体
AW209082 抗体
bHLHb21 抗体
bhlhb21 抗体
E2A 抗体
e2a 抗体
E12 抗体
E12/E47 抗体
E47 抗体
G12 抗体
ITF1 抗体
itf1 抗体
ME2 抗体
Pan1 抗体
Pan2 抗体
TCF-3 抗体
tcf3a 抗体
TCF7L1 抗体
Tcfe2a 抗体
tcfe2a 抗体
VDIR 抗体
vdir 抗体
XE3 抗体
xtcf-3 抗体
xtcf3 抗体
zgc:113045 抗体
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