(Transcription Elongation Factor A (SII)-Like 1 (TCEAL1))
This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. The encoded protein is similar to transcription elongation factor A/transcription factor SII and contains a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region. It may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform. [provided by RefSeq, Jul 2008].
Chung, Huang, Pu, Su, Huang, Chen, Hsueh: "Polymorphisms in cell cycle regulatory genes, urinary arsenic profile and urothelial carcinoma." in: Toxicology and applied pharmacology, Vol. 232, Issue 2, pp. 203-9, (2008) (PubMed).
Klos, Wyszomierski, Sun, Tan, Zhou, Li, Yang, Yin, Hittelman, Yu: "ErbB2 increases vascular endothelial growth factor protein synthesis via activation of mammalian target of rapamycin/p70S6K leading to increased angiogenesis and spontaneous metastasis of human breast cancer cells." in: Cancer research, Vol. 66, Issue 4, pp. 2028-37, (2006) (PubMed).
Aliases for TCEAL1 抗体
transcription elongation factor A like 1 (TCEAL1) 抗体 transcription elongation factor A (SII)-like 1 (Tceal1) 抗体 transcription elongation factor A like 1 (Tceal1) 抗体 0610011M09Rik 抗体 BC011290 抗体 p21 抗体 P21 抗体 pp21 抗体 SIIR 抗体