TCEAL1 抗体 (Middle Region)
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北京 101111
Quick Overview for TCEAL1 抗体 (Middle Region) (ABIN2776430)
抗原
See all TCEAL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- TCEAL1 Antibody - middle region
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序列
- EGLSRKDLFE GRPPMEQPPC GVGKHKLEEG SFKERLARSR PQFRGDIHGR
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预测反应
- Cow: 87%, Dog: 87%, Horse: 87%, Human: 87%, Mouse: 87%, Pig: 87%, Rabbit: 87%, Rat: 80%
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产品特性
- This is a rabbit polyclonal antibody against TCEAL1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human TCEAL1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP35748-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "ErbB2 increases vascular endothelial growth factor protein synthesis via activation of mammalian target of rapamycin/p70S6K leading to increased angiogenesis and spontaneous metastasis of human breast cancer cells." in: Cancer research, Vol. 66, Issue 4, pp. 2028-37, (2006) (PubMed).
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- TCEAL1 (Transcription Elongation Factor A (SII)-Like 1 (TCEAL1))
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别名
- TCEAL1
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背景
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Background Information: TCEAL1 is a member of the transcription elongation factor A (SII)-like (TCEAL) protein family. Members of this family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. TCEAL1 is similar to transcription elongation factor A/transcription factor SII and contains a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region. It may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA. This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. The encoded protein is similar to transcription elongation factor A/transcription factor SII and contains a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region. It may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform.
Gene Name: Transcription elongation factor A (SII)-like 1
Alternative Symbols: p21, SIIR, WEX9, pp21
Protein Name: Transcription elongation factor A protein-like 1
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分子量
- 19kDa
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基因ID
- 9338
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NCBI登录号
- NP_001006641
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UniProt
- Q15170
抗原
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