TAAR1 is a G protein-coupled receptor activated by trace amines. Trace amines are endogenous amine compounds that account for less than 1% of the biogenic amines in most brain regions (Bunzow et al., 2001 [PubMed 11723224]).[supplied by OMIM, Mar 2008].
Szumska, Qatato, Rehders, Führer, Biebermann, Grandy, Köhrle, Brix: "Trace Amine-Associated Receptor 1 Localization at the Apical Plasma Membrane Domain of Fisher Rat Thyroid Epithelial Cells Is Confined to Cilia." in: European thyroid journal, Vol. 4, Issue Suppl 1, pp. 30-41, (2015) (PubMed).
Reese, Bunzow, Arttamangkul, Sonders, Grandy: "Trace amine-associated receptor 1 displays species-dependent stereoselectivity for isomers of methamphetamine, amphetamine, and para-hydroxyamphetamine." in: The Journal of pharmacology and experimental therapeutics, Vol. 321, Issue 1, pp. 178-86, (2007) (PubMed).
Lindemann, Ebeling, Kratochwil, Bunzow, Grandy, Hoener: "Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors." in: Genomics, Vol. 85, Issue 3, pp. 372-85, (2005) (PubMed).