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SYN2 产品

(Synapsin II (SYN2))
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. The TIMP4 gene is located within an intron of this gene and is transcribed in the opposite direction. Mutations in this gene may be associated with abnormal presynaptic function and schizophrenia. Alternative splicing of this gene results in two transcripts. [provided by RefSeq, Jul 2008].

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Featured SYN2 Categories

SYN2 抗体

High quality antibodies with extensive validation data.

SYN2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

SYN2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SYN2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7239083
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ICC
Validations
  • (1)
  • (3)
Cat. No. ABIN1742207
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, ICC
Validations
  • (3)
Cat. No. ABIN5014371
Quantity 100 μL
Datasheet Datasheet

Recommended SYN2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959792
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959793
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6209133
Quantity 96 tests
Datasheet Datasheet

Recommended SYN2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321978
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3073642
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3123287
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SYN2 Products

Raphael, Webb, Gomez-Rivera, Chase Huizar, Gupta, Arulanandam, Wang, Haskins, Forsthuber: "Serum Neuroinflammatory Disease-Induced Central Nervous System Proteins Predict Clinical Onset of Experimental Autoimmune Encephalomyelitis." in: Frontiers in immunology, Vol. 8, pp. 812, (2017) (PubMed).

Acuna, Liu, Südhof: "How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs." in: Neuron, Vol. 91, Issue 4, pp. 792-807, (2016) (PubMed).

Jovasevic, Corcoran, Leaderbrand, Yamawaki, Guedea, Chen, Shepherd, Radulovic: "GABAergic mechanisms regulated by miR-33 encode state-dependent fear." in: Nature neuroscience, Vol. 18, Issue 9, pp. 1265-71, (2015) (PubMed).

Shulman, Stavsky, Fedorova, Mikulincer, Atias, Radinsky, Kahn, Slutsky, Gitler: "ATP binding to synaspsin IIa regulates usage and clustering of vesicles in terminals of hippocampal neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 3, pp. 985-98, (2015) (PubMed).

Chen, Yu, Huang, Yu, Zhu, Lam, Lam, Zhou: "Prenatal transfer of polybrominated diphenyl ethers (PBDEs) results in developmental neurotoxicity in zebrafish larvae." in: Environmental science & technology, Vol. 46, Issue 17, pp. 9727-34, (2012) (PubMed).

Petersohn, Schoch, Brinkmann, Thiel: "The human synapsin II gene promoter. Possible role for the transcription factor zif268/egr-1, polyoma enhancer activator 3, and AP2." in: The Journal of biological chemistry, Vol. 270, Issue 41, pp. 24361-9, (1995) (PubMed).

Ferreira, Kosik, Greengard, Han: "Aberrant neurites and synaptic vesicle protein deficiency in synapsin II-depleted neurons." in: Science (New York, N.Y.), Vol. 264, Issue 5161, pp. 977-9, (1994) (PubMed).

Thiel, Südhof, Greengard: "Synapsin II. Mapping of a domain in the NH2-terminal region which binds to small synaptic vesicles." in: The Journal of biological chemistry, Vol. 265, Issue 27, pp. 16527-33, (1990) (PubMed).

Südhof, Czernik, Kao, Takei, Johnston, Horiuchi, Kanazir, Wagner, Perin, De Camilli: "Synapsins: mosaics of shared and individual domains in a family of synaptic vesicle phosphoproteins." in: Science (New York, N.Y.), Vol. 245, Issue 4925, pp. 1474-80, (1989) (PubMed).

Synonyms and alternative names related to SYN2

synapsin II L homeolog (syn2.L), synapsin II (SYN2), synapsin IIa (syn2a), synapsin II S homeolog (syn2.S), synapsin-2 (EDI_190690), synapsin II (Syn2), 2900074L19Rik, AI836018, AI841723, MGC115109, syn1, syn2, SYN2, synII, SYNII, synIIa, SYNIIa, synIIb, SYNIIb, zgc:92311

Protein level used designations for SYN2

  • synapsin II
  • synapsin IIa
  • synapsin-2
  • synapsin2
  • synapsin-2-like
  • synapsin 2
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