SYCP1 产品
(Synaptonemal Complex Protein 1 (SYCP1))
Categories
Preferentially catalyzes the dephosphorylation of 'Ser- 5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
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Featured SYCP1 Categories
Recommended SYCP1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
IF, IHC, IHC (p), IHC (fro)
Validations
- (2)
- (2)
Cat. No.
ABIN540435
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN6257491
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Guinea Pig, Human, Mouse, Rat
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN6748640
Quantity
100 μL
Datasheet
Datasheet
Recommended SYCP1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3095752
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3135525
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2733024
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our SYCP1 Products
: "CXXC1 is not essential for normal DNA double-strand break formation and meiotic recombination in mouse." in: PLoS genetics, Vol. 14, Issue 10, pp. e1007657, (2019) (PubMed).: "Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination." in: Nature communications, Vol. 9, Issue 1, pp. 3961, (2019) (PubMed).
: "Mouse DCUN1D1 (SCCRO) is required for spermatogenetic individualization." in: PLoS ONE, Vol. 14, Issue 1, pp. e0209995, (2019) (PubMed).
: "The pericentromeric heterochromatin of homologous chromosomes remains associated after centromere pairing dissolves in mouse spermatocyte meiosis." in: Chromosoma, (2019) (PubMed).
: "Cell-type-specific genomics reveals histone modification dynamics in mammalian meiosis." in: Nature communications, Vol. 10, Issue 1, pp. 3821, (2019) (PubMed).
: "FBXO47 regulates telomere-inner nuclear envelope integration by stabilizing TRF2 during meiosis." in: Nucleic acids research, Vol. 47, Issue 22, pp. 11755-11770, (2019) (PubMed).
: "Dual roles of TRF1 in tethering telomeres to the nuclear envelope and protecting them from fusion during meiosis." in: Cell death and differentiation, Vol. 25, Issue 6, pp. 1174-1188, (2018) (PubMed).
: "SHOC1 is a ERCC4-(HhH)2-like protein, integral to the formation of crossover recombination intermediates during mammalian meiosis." in: PLoS genetics, Vol. 14, Issue 5, pp. e1007381, (2018) (PubMed).
: "A study of meiomitosis and novel pathways of genomic instability in cutaneous T-cell lymphomas (CTCL)." in: Oncotarget, Vol. 9, Issue 102, pp. 37647-37661, (2018) (PubMed).
: "Meiotic Knockdown and Complementation Reveals Essential Role of RAD51 in Mouse Spermatogenesis." in: Cell reports, Vol. 18, Issue 6, pp. 1383-1394, (2017) (PubMed).
Synonyms and alternative names related to SYCP1
synaptonemal complex protein 1 (SYCP1), synaptonemal complex protein 1 (sycp1), Myosin heavy chain-related protein (ZYP1a), synaptonemal complex protein 1 (Sycp1), CT8, HOM-TES-14, SCP-1, SCP1, SYCP1, sycp1, syn1, T16E15.12, T16E15_12, ZYP1Protein level used designations for SYCP1
- SCP-1
- cancer/testis antigen 8
- synaptonemal complex protein 1
- synaptonemal complex protein 1-like
- A coiled-coil related protein specific for synapsed regions of meiotic prophase chromosomes
- Meiotic chromosome synaptic protein
- LOW QUALITY PROTEIN: synaptonemal complex protein 1
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