Nanog 蛋白
(Nanog Homeobox (NANOG))
Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'- [CG][GA][CG]C[GC]ATTAN[GC]-3'. When overexpressed, promotes cells to enter into S phase and proliferation (By similarity).
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15 results
custom-made
NANOG
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
NANOG
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
SDS, WB, Imm, PC
custom-made
NANOG
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
NANOG
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
NANOG
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
>95 % , as determined by SDS-PAGE and HPLC
NANOG
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
NANOG
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
< 95 % by SDS-PAGE gel and HPLC analyses.
Active
Aliases for Nanog 蛋白
Nanog homeobox (Nanog) 蛋白Nanog homeobox (NANOG) 蛋白
nanog homeobox (nanog) 蛋白
2410002E02Rik 蛋白
ecat4 蛋白
ENK 蛋白
hacp 蛋白
NANOG 蛋白
wu:fd19e04 蛋白
wu:fd20a07 蛋白
zgc:193933 蛋白
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