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STXBP5 产品

(Syntaxin Binding Protein 5 (Tomosyn) (STXBP5))

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Syntaxin 1 is a component of the 7S and 20S SNARE complexes which are involved in docking and fusion of synaptic vesicles with the presynaptic plasma membrane. This gene encodes a syntaxin 1 binding protein. In rat, a similar protein dissociates syntaxin 1 from the Munc18/n-Sec1/rbSec1 complex to form a 10S complex, an intermediate which can be converted to the 7S SNARE complex. Thus this protein is thought to be involved in neurotransmitter release by stimulating SNARE complex formation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

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Featured STXBP5 Categories

STXBP5 抗体

High quality antibodies with extensive validation data.

STXBP5 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended STXBP5 抗体

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Cat. No. ABIN7171265
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Cat. No. ABIN1742382
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Cat. No. ABIN566817
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Recommended STXBP5 ELISA试剂盒

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Reactivity Human
Analytical Method Quantitative Sandwich ELISA
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Cat. No. ABIN6233066
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Recommended STXBP5 蛋白

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Cat. No. ABIN3095727
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Latest Publications for our STXBP5 Products

Burgalossi, Jung, Meyer, Jockusch, Jahn, Taschenberger, OConnor, Nishiki, Takahashi, Brose, Rhee: "SNARE protein recycling by αSNAP and βSNAP supports synaptic vesicle priming." in: Neuron, Vol. 68, Issue 3, pp. 473-87, (2010) (PubMed).

Yokoyama, Shirataki, Sakisaka, Takai: "Three splicing variants of tomosyn and identification of their syntaxin-binding region." in: Biochemical and biophysical research communications, Vol. 256, Issue 1, pp. 218-22, (1999) (PubMed).

Fujita, Shirataki, Sakisaka, Asakura, Ohya, Kotani, Yokoyama, Nishioka, Matsuura, Mizoguchi, Scheller, Takai: "Tomosyn: a syntaxin-1-binding protein that forms a novel complex in the neurotransmitter release process." in: Neuron, Vol. 20, Issue 5, pp. 905-15, (1998) (PubMed).

Synonyms and alternative names related to STXBP5

syntaxin binding protein 5 (STXBP5), syntaxin binding protein 5 (tomosyn) (Stxbp5), syntaxin binding protein 5 (Stxbp5), 0710001E20Rik, 4930565N16Rik, AW742610, LGL3, LLGL3, mKIAA1006, Nbla04300

Protein level used designations for STXBP5

  • lethal(2) giant larvae protein homolog 3
  • putative protein product of Nbla04300
  • syntaxin-binding protein 5
  • tomosyn
  • tomosyn-1
  • tomosyn 1
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