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STAU1/Staufen 产品

(Staufen Double-Stranded RNA Binding Protein 1 (STAU1))

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Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR. [provided by RefSeq, Jul 2008].

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Featured STAU1/Staufen Categories

STAU1/Staufen 抗体

High quality antibodies with extensive validation data.

STAU1/Staufen ELISA试剂盒

Reliable ELISA kits for a wide range of species.

STAU1/Staufen 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended STAU1/Staufen 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (cc), IF (p), IHC (p)
Validations
  • (1)
  • (3)
Cat. No. ABIN1385730
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
Cat. No. ABIN563040
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7150628
Quantity 100 μg
Datasheet Datasheet

Recommended STAU1/Staufen ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6207800
Quantity 96 tests
Datasheet Datasheet

Recommended STAU1/Staufen 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321612
Quantity 25 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3120259
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5505776
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our STAU1/Staufen Products

Paul, Dansithong, Figueroa, Scoles, Pulst: "Staufen1 links RNA stress granules and autophagy in a model of neurodegeneration." in: Nature communications, Vol. 9, Issue 1, pp. 3648, (2018) (PubMed).

Shiihashi, Ito, Arai, Kobayashi, Hayashi, Otsuka, Nakajima, Yuzaki, Itohara, Suzuki: "Dendritic Homeostasis Disruption in a Novel Frontotemporal Dementia Mouse Model Expressing Cytoplasmic Fused in Sarcoma." in: EBioMedicine, Vol. 24, pp. 102-115, (2018) (PubMed).

de Morrée, van Velthoven, Gan, Salvi, Klein, Akimenko, Quarta, Biressi, Rando: "Staufen1 inhibits MyoD translation to actively maintain muscle stem cell quiescence." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 43, pp. E8996-E9005, (2017) (PubMed).

Synonyms and alternative names related to STAU1/Staufen

staufen double-stranded RNA binding protein 1 (STAU1), staufen (stau), staufen double-stranded RNA binding protein 1 (stau1), RNA binding protein homolog (STAUFEN), staufen (RNA binding protein) homolog 1 (Drosophila) (Stau1), staufen double-stranded RNA binding protein 1 (Stau1), staufen double-stranded RNA binding protein 1 L homeolog (stau1.L), 5830401L18Rik, AW549911, C85792, CG5753, DKFZp459A0124, Dmel\\CG5753, Dmstau, dStau, fi67e05, MGC145034, STAU, Stau, stau, STAU1, Stauf, Staufen, Staufen1, wu:fi67e05, XStau, XStau1, zgc:77271

Protein level used designations for STAU1/Staufen

  • staufen, RNA binding protein, homolog 1 (Drosophila)
  • double-stranded RNA-binding protein Staufen homolog 1
  • double-stranded RNA-binding protein Staufen homolog 1-like
  • CG5753-PA
  • CG5753-PB
  • CG5753-PC
  • stau-PA
  • stau-PB
  • stau-PC
  • stauffen
  • staufen, RNA binding protein, homolog 1
  • Staufen 1
  • staufen
  • RNA binding protein homolog
  • staufen RNA binding protein homolog 1
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