(Signal Transducer and Activator of Transcription 5A (STAT5A))
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq, Jul 2008].
custom-made
STAT5A
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
custom-made
STAT5A
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
signal transducer and activator of transcription 5A (STAT5A) 蛋白 signal transducer and activator of transcription 5A (Stat5a) 蛋白 signal transducer and activator of transcription 5a (stat5a) 蛋白 signal transducer and activator of transcription 5A (LOC100348518) 蛋白 signal transducer and activator of transcription 5A (LOC100716811) 蛋白 AA959963 蛋白 MGF 蛋白 STAT5 蛋白 Stat5 蛋白 stat5 蛋白 STAT5A 蛋白 STAT5A/MGF 蛋白 stat5b 蛋白 STATA5 蛋白