STAT4 抗体
(Signal Transducer and Activator of Transcription 4 (STAT4))
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011].
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95 results
STAT4
适用: 人, 大鼠, 猴, Pig, 犬, 兔, 马
WB, IHC, IHC (p)
宿主: 兔
Polyclonal
unconjugated
2 images
STAT4
适用: 人, 小鼠, 大鼠, 猴
WB, ELISA, IP, IHC (p)
宿主: 兔
Polyclonal
unconjugated
1 image
Latest Publications for our STAT4 抗体
: "A guanidine-rich regulatory oligodeoxynucleotide improves type-2 diabetes in obese mice by blocking T-cell differentiation." in: EMBO molecular medicine, Vol. 4, Issue 10, pp. 1112-25, (2012) (PubMed).: "Temporal induction pattern of STAT4 target genes defines potential for Th1 lineage-specific programming." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 6, pp. 3839-47, (2009) (PubMed).
: "High basal STAT4 balanced by STAT1 induction to control type 1 interferon effects in natural killer cells." in: The Journal of experimental medicine, Vol. 204, Issue 10, pp. 2383-96, (2007) (PubMed).
: "Interferon alpha but not interleukin 12 activates STAT4 signaling in human vascular endothelial cells." in: The Journal of biological chemistry, Vol. 279, Issue 25, pp. 26789-96, (2004) (PubMed).
: "PIASx is a transcriptional co-repressor of signal transducer and activator of transcription 4." in: The Journal of biological chemistry, Vol. 278, Issue 24, pp. 21327-30, (2003) (PubMed).
: "Signaling through the JAK/STAT pathway, recent advances and future challenges." in: Gene, Vol. 285, Issue 1-2, pp. 1-24, (2002) (PubMed).
: "Activated STAT4 and a functional role for IL-12 in human Peyer's patches." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 1, pp. 300-7, (2002) (PubMed).
: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).
: "Importance of the MKK6/p38 pathway for interleukin-12-induced STAT4 serine phosphorylation and transcriptional activity." in: Blood, Vol. 96, Issue 5, pp. 1844-52, (2000) (PubMed).
Aliases for STAT4 抗体
signal transducer and activator of transcription 4 (STAT4) 抗体signal transducer and activator of transcription 4 (stat4) 抗体
signal transducer and activator of transcription 4 (Stat4) 抗体
SLEB11 抗体
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