The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X\;18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
Smith, Cronk, Lang, McNeel: "Expression and immunotherapeutic targeting of the SSX family of cancer-testis antigens in prostate cancer." in: Cancer research, Vol. 71, Issue 21, pp. 6785-95, (2011) (PubMed).
Aliases for SSX5 抗体
putative protein SSX6 (LOC612524) 抗体 synovial sarcoma, X breakpoint 5 (SSX5) 抗体 SSX family member 5 (SSX5) 抗体