SPTLC1 抗体
(serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
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63 results
SPTLC1
适用: 人, Cow, 兔, 猴, Bat, Pig, 绵羊
WB, IHC, IHC (p)
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our SPTLC1 抗体
: "Transcriptional Differences in Lipid-Metabolizing Enzymes in Murine Sebocytes Derived from Sebaceous Glands of the Skin and Preputial Glands." in: International journal of molecular sciences, Vol. 22, Issue 21, (2021) (PubMed).: "Serine palmitoyltransferase subunit 1 is present in the endoplasmic reticulum, nucleus and focal adhesions, and functions in cell morphology." in: Biochimica et biophysica acta, Vol. 1791, Issue 8, pp. 746-56, (2009) (PubMed).
: "Apoptotic sphingolipid signaling by ceramides in lung endothelial cells." in: American journal of respiratory cell and molecular biology, Vol. 38, Issue 6, pp. 639-46, (2008) (PubMed).
: "Permeability barrier disruption increases the level of serine palmitoyltransferase in human epidermis." in: The Journal of investigative dermatology, Vol. 119, Issue 5, pp. 1048-52, (2002) (PubMed).
: "Mutations in SPTLC1, encoding serine palmitoyltransferase, long chain base subunit-1, cause hereditary sensory neuropathy type I." in: Nature genetics, Vol. 27, Issue 3, pp. 309-12, (2001) (PubMed).
: "Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum." in: Brain research, Vol. 909, Issue 1-2, pp. 187-93, (2001) (PubMed).
: "A mammalian homolog of the yeast LCB1 encodes a component of serine palmitoyltransferase, the enzyme catalyzing the first step in sphingolipid synthesis." in: The Journal of biological chemistry, Vol. 272, Issue 51, pp. 32108-14, (1998) (PubMed).
: "Human and murine serine-palmitoyl-CoA transferase--cloning, expression and characterization of the key enzyme in sphingolipid synthesis." in: European journal of biochemistry / FEBS, Vol. 249, Issue 1, pp. 239-47, (1997) (PubMed).
Aliases for SPTLC1 抗体
serine palmitoyltransferase 1 (SPT1) 抗体serine palmitoyltransferase 1 (AFUA_6G00300) 抗体
Serine palmitoyltransferase 1 (PAS_FragB_0040) 抗体
serine palmitoyltransferase long chain base subunit 1 (SPTLC1) 抗体
serine palmitoyltransferase, long chain base subunit 1 (sptlc1) 抗体
serine palmitoyltransferase, long chain base subunit 1 L homeolog (sptlc1.L) 抗体
serine palmitoyltransferase, long chain base subunit 1 (Sptlc1) 抗体
serine palmitoyltransferase long chain base subunit 1 (Sptlc1) 抗体
Afu6g00300 抗体
ATSPT1 抗体
AW552086 抗体
C77762 抗体
E030036H05 抗体
HSAN1 抗体
HSN1 抗体
LBC1 抗体
LCB1 抗体
Lcb1 抗体
RGD1306617 抗体
SERINE PALMITOYLTRANSFERASE 1 抗体
serine palmitoyltransferase 1 抗体
SPT1 抗体
Spt1 抗体
SPTI 抗体
wu:fc75h04 抗体
wu:fp41c08 抗体
zgc:112247 抗体
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