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SOCS2 蛋白

(Suppressor of Cytokine Signaling 2 (SOCS2))
This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor. The protein encoded by this gene interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling. This gene has pseudogenes on chromosomes 20 and 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012].
SOCS2 Protein (AA 1-198) (GST tag) SOCS2 Protein (AA 1-198) (GST tag) SOCS2 Protein (AA 1-198) (GST tag) (ABIN1320927)

SOCS2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA

SOCS2 Protein (AA 99-198) (GST tag) SOCS2 Protein (AA 99-198) (GST tag) SOCS2 Protein (AA 99-198) (GST tag) (ABIN1320929)

SOCS2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA

SOCS2 Protein (AA 1-198) (Strep Tag) SOCS2 Protein (AA 1-198) (Strep Tag) SOCS2 Protein (AA 1-198) (Strep Tag) (ABIN3077005)

Crystallography grade SOCS2 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA

SOCS2 蛋白 by Grade

Find SOCS2 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

SOCS2 蛋白 by Origin

Find SOCS2 蛋白 for a variety of species such as anti-Human SOCS2, anti-Rat SOCS2, anti-Sheep SOCS2. The species listed below are among those available. Click on a link to go to the corresponding products.

SOCS2 蛋白 by Source

Here you will find SOCS2 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

SOCS2 蛋白 by 蛋白类型

Here you can find SOCS2 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

SOCS2 蛋白 by 应用范围

Find SOCS2 蛋白 validated for a specific application such as ELISA, WB, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular SOCS2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1320927
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320929
Quantity 2 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3077005
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3131673
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505230
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7408915
Quantity 100 μg
Datasheet Datasheet
Reactivity Sheep
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2854101
Quantity 100 μg
Datasheet Datasheet
Reactivity Sheep
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2854104
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1475740
Quantity 1 mg
Datasheet Datasheet
Reactivity Pig
Source Yeast
Validations
Cat. No. ABIN1613554
Quantity 1 mg
Datasheet Datasheet
Reactivity Cow
Source Yeast
Validations
Cat. No. ABIN1613612
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SOCS2 蛋白

Sen, Peng, Woods, Wistuba, Bell, El-Naggar, Lai, Johnson: "STAT5A-mediated SOCS2 expression regulates Jak2 and STAT3 activity following c-Src inhibition in head and neck squamous carcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 18, Issue 1, pp. 127-39, (2012) (PubMed).

Aliases for SOCS2 蛋白

suppressor of cytokine signaling 2 (SOCS2) 蛋白
suppressor of cytokine signaling 1 (Socs1) 蛋白
suppressor of cytokine signaling 2 (Socs2) 蛋白
suppressor of cytokine signaling 2 (socs2) 蛋白
death domain-containing protein CRADD (LOC100716104) 蛋白
suppressor of cytokine signaling 2 S homeolog (socs2.S) 蛋白
8030460M17 蛋白
AI527257 蛋白
AW108012 蛋白
CIS2 蛋白
cis2 蛋白
Cish1 蛋白
Cish2 蛋白
cish2 蛋白
Cradd 蛋白
D130043N08Rik 蛋白
hg 蛋白
JAB 蛋白
si:dkey-202b22.1 蛋白
Socs-1 蛋白
SOCS-2 蛋白
Socs-2 蛋白
socs-2 蛋白
socs2 蛋白
Socs2 蛋白
SSI-2 蛋白
ssi-2 蛋白
SSI2 蛋白
ssi2 蛋白
STATI2 蛋白
stati2 蛋白
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