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SNCAIP 产品

(Synuclein, alpha Interacting Protein (SNCAIP))

Categories

This gene encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinson's disease. Alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of only two have been determined. [provided by RefSeq, Jul 2011].

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Featured SNCAIP Categories

SNCAIP 抗体

High quality antibodies with extensive validation data.

SNCAIP ELISA试剂盒

Reliable ELISA kits for a wide range of species.

SNCAIP 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SNCAIP 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7171209
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (2)
Cat. No. ABIN736163
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN564163
Quantity 100 μg
Datasheet Datasheet

Recommended SNCAIP ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959832
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959833
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Sandwich ELISA
Validations
Cat. No. ABIN418528
Quantity 96 tests
Datasheet Datasheet

Recommended SNCAIP 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320778
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320780
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3095595
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SNCAIP Products

Büttner, Delay, Franssens, Bammens, Ruli, Zaunschirm, de Oliveira, Outeiro, Madeo, Buée, Galas, Winderickx: "Synphilin-1 enhances ?-synuclein aggregation in yeast and contributes to cellular stress and cell death in a Sir2-dependent manner." in: PLoS ONE, Vol. 5, Issue 10, pp. e13700, (2010) (PubMed).

Tanaka, Kim, Lee, Junn, Iwatsubo, Mouradian: "Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotective." in: The Journal of biological chemistry, Vol. 279, Issue 6, pp. 4625-31, (2004) (PubMed).

Lee, Tanaka, Park, Lee, Kim, Junn, Lee, Mouradian: "Casein kinase II-mediated phosphorylation regulates alpha-synuclein/synphilin-1 interaction and inclusion body formation." in: The Journal of biological chemistry, Vol. 279, Issue 8, pp. 6834-9, (2004) (PubMed).

Nagano, Yamashita, Takahashi, Kishida, Nakamura, Iseki, Hattori, Mizuno, Kikuchi, Matsumoto: "Siah-1 facilitates ubiquitination and degradation of synphilin-1." in: The Journal of biological chemistry, Vol. 278, Issue 51, pp. 51504-14, (2003) (PubMed).

Synonyms and alternative names related to SNCAIP

synuclein alpha interacting protein (SNCAIP), synuclein alpha interacting protein (sncaip), synuclein, alpha interacting protein (Sncaip), synuclein alpha interacting protein (Sncaip), synuclein, alpha interacting protein (synphilin) (Sncaip), 2810407O15Rik, 4933427B05Rik, BB104594, LOC100221074, MGC88953, sncaip, SNCAIP, Sph1, SYPH1, Syph1

Protein level used designations for SNCAIP

  • synuclein, alpha interacting protein
  • synuclein, alpha interacting protein (synphilin)
  • synphilin-1-like
  • alpha-synuclein-interacting protein
  • synphilin-1
  • synuclein alpha interacting protein
  • synphilin-1 variant 1e
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