SNAPIN 产品
(SNAP-Associated Protein (SNAPIN))
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The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012].
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Featured SNAPIN Categories
SNAPIN 抗体
High quality antibodies with extensive validation data.
SNAPIN ELISA试剂盒
Reliable ELISA kits for a wide range of species.
SNAPIN 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SNAPIN 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (3)
Cat. No.
ABIN525253
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7441457
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN525251
Quantity
50 μL
Datasheet
Datasheet
Recommended SNAPIN ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959541
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1158381
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1158382
Quantity
96 tests
Datasheet
Datasheet
Recommended SNAPIN 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN666875
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320770
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320772
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our SNAPIN Products
: "Annexin A1 complex mediates oxytocin vesicle transport." in: Journal of neuroendocrinology, Vol. 25, Issue 12, pp. 1241-54, (2014) (PubMed).: "LRRK2 phosphorylates Snapin and inhibits interaction of Snapin with SNAP-25." in: Experimental & molecular medicine, Vol. 45, pp. e36, (2013) (PubMed).
: "Snapin recruits dynein to BDNF-TrkB signaling endosomes for retrograde axonal transport and is essential for dendrite growth of cortical neurons." in: Cell reports, Vol. 2, Issue 1, pp. 42-51, (2012) (PubMed).
: "The role for HNF-1beta-targeted collectrin in maintenance of primary cilia and cell polarity in collecting duct cells." in: PLoS ONE, Vol. 2, Issue 5, pp. e414, (2007) (PubMed).
: "Molecular anatomy of a trafficking organelle." in: Cell, Vol. 127, Issue 4, pp. 831-46, (2006) (PubMed).
: "Reinvestigation of the role of snapin in neurotransmitter release." in: The Journal of biological chemistry, Vol. 279, Issue 25, pp. 26251-6, (2004) (PubMed).
Synonyms and alternative names related to SNAPIN
SNAP associated protein (SNAPIN), SNAP-associated protein L homeolog (snapin.L), SNAP-associated protein (snapin), SNAP-associated protein (Snapin), 25kDa, AA407989, AV026596, BLOC1S7, Bloc1s7, BLOS7, si:dkey-222b8.2, Snap25bp, SNAPAP, Snapap, SNAPINProtein level used designations for SNAPIN
- SNAP-associated protein
- SNARE-associated protein Snapin
- BLOC-1 subunit 7
- SNAP-25-binding protein
- SNARE associated protein snapin
- biogenesis of lysosomal organelles complex-1, subunit 7
- biogenesis of lysosome-related organelles complex 1 subunit 7
- synaptosomal-associated protein 25-binding protein
- synaptosomal-associated protein 25 binding protein
- synaptosomal-associated protein, 25 kDa, binding protein
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