The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012].
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Aliases for SNAPIN 抗体
SNAP associated protein (SNAPIN) 抗体 SNAP-associated protein L homeolog (snapin.L) 抗体 SNAP-associated protein (snapin) 抗体 SNAP-associated protein (Snapin) 抗体 25kDa 抗体 AA407989 抗体 AV026596 抗体 BLOC1S7 抗体 Bloc1s7 抗体 BLOS7 抗体 si:dkey-222b8.2 抗体 Snap25bp 抗体 SNAPAP 抗体 Snapap 抗体 SNAPIN 抗体