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SMG7 蛋白

(Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (SMG7))
This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD)\; a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2011].

2 results :

SMG7 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % SDS
产品编号 ABIN5710916
 
SMG7 宿主: 小鼠 宿主: 酵母菌 Recombinant > 90 % SDS
产品编号 ABIN5714104
 
  • 类型 Protein
    • Protein
  • 应用范围
    • SDS-PAGE (SDS)
  • 适用
    • Mouse
  • 图像
  • 抗体来源
    • Escherichia coli (E. coli)
    • Yeast
  • 抗原表位
    • AA 19-550
    • partial
  • 标记
    • His tag
    • 非结合性
  • 蛋白类型
    • Recombinant
  • Format
    • Liquid
  • Supplier
    • Signalway

Aliases for SMG7 蛋白

Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) (Smg7) 蛋白
SMG7, nonsense mediated mRNA decay factor (SMG7) 蛋白
9430023P16Rik 蛋白
C1orf16 蛋白
EST1C 蛋白
mKIAA0250 蛋白
SGA56M 蛋白
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