(Sperm Mitochondria Associated Cysteine Rich Protein (SMCP))
Sperm mitochondria differ in morphology and subcellular localization from those of somatic cells. They are elongated, flattened, and arranged circumferentially to form a helical coiled sheath in the midpiece of the sperm flagellum. The protein encoded by this gene localizes to the capsule associated with the mitochondrial outer membranes and is thought to function in the organization and stabilization of the helical structure of the sperm's mitochondrial sheath. [provided by RefSeq, Jul 2008].
Djureinovic, Fagerberg, Hallström, Danielsson, Lindskog, Uhlén, Pontén: "The human testis-specific proteome defined by transcriptomics and antibody-based profiling." in: Molecular human reproduction, Vol. 20, Issue 6, pp. 476-88, (2014) (PubMed).
Nayernia, Adham, Burkhardt-Göttges, Neesen, Rieche, Wolf, Sancken, Kleene, Engel: "Asthenozoospermia in mice with targeted deletion of the sperm mitochondrion-associated cysteine-rich protein (Smcp) gene." in: Molecular and cellular biology, Vol. 22, Issue 9, pp. 3046-52, (2002) (PubMed).