SMC5 抗体
(Structural Maintenance of Chromosomes 5 (SMC5))
Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Required for recruitment of telomeres to PML nuclear bodies. Required for sister chromatid cohesion during prometaphase and mitotic progression\; the function seems to be independent of SMC6 (By similarity).
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Latest Publications for our SMC5 抗体
: "SMC5/6 is required for the formation of segregation-competent bivalent chromosomes during meiosis I in mouse oocytes." in: Development (Cambridge, England), Vol. 144, Issue 9, pp. 1648-1660, (2017) (PubMed).: "Specialized compartments of cardiac nuclei exhibit distinct proteomic anatomy." in: Molecular & cellular proteomics : MCP, Vol. 10, Issue 1, pp. M110.000703, (2011) (PubMed).
: "Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 37, pp. 15726-31, (2009) (PubMed).
: "Nse1 RING-like domain supports functions of the Smc5-Smc6 holocomplex in genome stability." in: Molecular biology of the cell, Vol. 19, Issue 10, pp. 4099-109, (2008) (PubMed).
Aliases for SMC5 抗体
structural maintenance of chromosomes 5 (SMC5) 抗体structural maintenance of chromosomes 5 (smc5) 抗体
structural maintenance of chromosomes 5 (Smc5) 抗体
structural maintenance of chromosomes 5 S homeolog (smc5.S) 抗体
F1N13.60 抗体
F1N13_60 抗体
mKIAA0594 抗体
MLZ-453 抗体
mSMC5 抗体
SMC-5 抗体
SMC5L1 抗体
Smc5l1 抗体
structural maintenance of chromosomes 5 抗体
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