SLCO1B1 产品
(Solute Carrier Organic Anion Transporter Family, Member 1B1 (SLCO1B1))
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This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function. [provided by RefSeq, Mar 2009].
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Featured SLCO1B1 Categories
SLCO1B1 抗体
High quality antibodies with extensive validation data.
SLCO1B1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SLCO1B1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7170287
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IF, ICC
Validations
- (3)
Cat. No.
ABIN6257509
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (3)
Cat. No.
ABIN653562
Quantity
400 μL
Datasheet
Datasheet
Recommended SLCO1B1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7555560
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320553
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7579573
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SLCO1B1 Products
: "Role of OATP transporters in steroid uptake by prostate cancer cells in vivo." in: Prostate cancer and prostatic diseases, (2016) (PubMed).: "Quantification of proteins by flow cytometry: Quantification of human hepatic transporter P-gp and OATP1B1 using flow cytometry and mass spectrometry." in: Methods (San Diego, Calif.), Vol. 82, pp. 38-46, (2015) (PubMed).
: "Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition." in: Genome research, Vol. 22, Issue 1, pp. 1-8, (2012) (PubMed).
: "Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters." in: American journal of physiology. Cell physiology, Vol. 296, Issue 3, pp. C570-82, (2009) (PubMed).
: "Transport of fluorescent chenodeoxycholic acid via the human organic anion transporters OATP1B1 and OATP1B3." in: Journal of lipid research, Vol. 47, Issue 6, pp. 1196-202, (2006) (PubMed).
: "Detection of the human organic anion transporters SLC21A6 (OATP2) and SLC21A8 (OATP8) in liver and hepatocellular carcinoma." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 83, Issue 4, pp. 527-38, (2003) (PubMed).
Synonyms and alternative names related to SLCO1B1
solute carrier organic anion transporter family member 1B1 (SLCO1B1), solute carrier organic anion transporter family member 1B1 (LOC100011628), solute carrier organic anion transporter family member 1B1 (LOC100448597), HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6, SLCO1B1Protein level used designations for SLCO1B1
- OATP-2
- liver-specific organic anion transporter 1
- sodium-independent organic anion-transporting polypeptide 2
- solute carrier family 21 (organic anion transporter), member 6
- solute carrier family 21 member 6
- solute carrier organic anion transporter family member 1B1
- solute carrier organic anion transporter family, member 1B1
- solute carrier organic anion transporter family member 1B1-like
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