(Solute Carrier Family 17 (Anion/Sugar Transporter), Member 4 (SLC17A4))
Phosphate homeostasis is maintained by regulating intake, intestinal absorption, bone deposition and resorption, and renal excretion of phosphate. The central molecule in the control of phosphate excretion from the kidney is the sodium/phosphate cotransporter NPT1 (SLC17A1\; MIM 182308), which is located in the renal proximal tubule. NPT1 uses the transmembrane electrochemical potential gradient of sodium to transport phosphate across the cell membrane. SLC17A4 is a similar sodium/phosphate cotransporter in the intestinal mucosa that plays an important role in the absorption of phosphate from the intestine (summary by Shibui et al., 1999 [PubMed 10319585]).[supplied by OMIM, Feb 2011].
Elmariah, Gunn: "Kinetic evidence that the Na-PO4 cotransporter is the molecular mechanism for Na/Li exchange in human red blood cells." in: American journal of physiology. Cell physiology, Vol. 285, Issue 2, pp. C446-56, (2003) (PubMed).
Aliases for SLC17A4 抗体
solute carrier family 17 member 4 (SLC17A4) 抗体 solute carrier family 17 member 3 (SLC17A3) 抗体 solute carrier family 17 (sodium phosphate), member 4 (Slc17a4) 抗体 solute carrier family 17, member 4 (Slc17a4) 抗体 9130214H05Rik 抗体 KAIA2138 抗体 SLC17A4 抗体