This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein binds each steroid molecule as a dimer formed from identical or nearly identical monomers. The use of alternate promoters and alternatively spliced transcripts have been described. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009].
Hauptmann, Metzger, Schnitzbauer, Cuilleron, Mappus, Luppa: "Syntheses and ligand-binding studies of 1 alpha- and 17 alpha-aminoalkyl dihydrotestosterone derivatives to human sex hormone-binding globulin." in: Steroids, Vol. 68, Issue 7-8, pp. 629-39, (2003) (PubMed).
Aliases for SHBG 蛋白
sex hormone binding globulin (SHBG) 蛋白 sex hormone binding globulin (Shbg) 蛋白 sex hormone-binding globulin (shbg) 蛋白 sex hormone binding globulin L homeolog (shbg.L) 蛋白 ABP 蛋白 Abpa 蛋白 SBP 蛋白 shbg 蛋白 shbgl 蛋白 TEBG 蛋白 wu:fb66h07 蛋白 wu:fd55b08 蛋白 zgc:123063 蛋白