SHC1 蛋白
(SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1))
This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011].
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custom-made
SHC1
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
SHC1
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
WB, SDS, PC, Imm
custom-made
SHC1
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
Aliases for SHC1 蛋白
SHC adaptor protein 1 (SHC1) 蛋白Shc1p (SHC1) 蛋白
squalene--hopene cyclase (shc1) 蛋白
SHC adaptor protein 1 (Shc1) 蛋白
SHC (Src homology 2 domain containing) transforming protein 1 (shc1) 蛋白
SHC (Src homology 2 domain containing) transforming protein 1 L homeolog (shc1.L) 蛋白
src homology 2 domain-containing transforming protein C1 (Shc1) 蛋白
p66 蛋白
P66shc 蛋白
p66shc 蛋白
SHC 蛋白
shc 蛋白
Shc 蛋白
SHC1 蛋白
SHCA 蛋白
ShcA 蛋白
si:dkey-246i14.4 蛋白
wu:fc10h03 蛋白
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