This gene encodes an adaptor protein thought to function in T-cell signal transduction. A related protein in mouse is responsible for the activation of lymphocyte-specific protein-tyrosine kinase and functions in downstream signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010].
Cao, Sun, Zhang, Qian, Li, Guo, Zhang: "Adenovirus-mediated bone morphogenetic protein-2 promotes osteogenic differentiation in human mesenchymal stem cells in vitro." in: Experimental and therapeutic medicine, Vol. 14, Issue 1, pp. 377-382, (2017) (PubMed).
Moussa, Abrahamsen, Fodil, Gopalakrishnan, Mancini, Dissen, Sæther, Wiltshire, Boivin, Caignard, Spurkland, Vidal: "Reduced MCMV Δm157 viral clearance in the absence of TSAd." in: Scientific reports, Vol. 5, pp. 9219, (2015) (PubMed).
Pandya, Leergaard, Dissen, Haraldsen, Spurkland: "Expression of the T cell-specific adapter protein in human tissues." in: Scandinavian journal of immunology, Vol. 80, Issue 3, pp. 169-79, (2014) (PubMed).