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SH2D1A 蛋白

(SH2 Domain Containing 1A (SH2D1A))
This gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells. This protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in this gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

16 results

custom-made SH2D1A 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7546049
 
custom-made SH2D1A 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7562684
 
SH2D1A 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
产品编号 ABIN7125076
 
SH2D1A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
产品编号 ABIN1319861
 
SH2D1A 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319330
 
SH2D1A 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, Imm, PC
产品编号 ABIN7405861
 
SH2D1A 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 94 % as determined by reducing SDS-PAGE. Active
产品编号 ABIN7317640
 
SH2D1A 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % pure SDS
产品编号 ABIN2131822
 
custom-made SH2D1A 宿主: 小鼠 宿主: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA
产品编号 ABIN3132254
 
custom-made SH2D1A 宿主: 人 宿主: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA
产品编号 ABIN3076886
 
SH2D1A 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2731954
 
SH2D1A 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, ELISA, IP
产品编号 ABIN3011636
 
SH2D1A 宿主: 大鼠 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN7586144
 
SH2D1A 宿主: Cow 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN7589389
 
SH2D1A 宿主: Saguinus oedipus 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1645601
 
SH2D1A 宿主: 猕猴 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1675967
 
  • 类型 Protein
    • Protein
  • 应用范围
    • ELISA
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Immunogen (Imm)
    • Immunoprecipitation (IP)
    • Positive Control (PC)
    • Standard (STD)
  • 适用
    • Human
    • Mouse
    • Cow
    • Rat
    • Rhesus Monkey
    • Saguinus oedipus
  • 图像
  • Carrier free only
  • 抗体来源
    • Escherichia coli (E. coli)
    • Yeast
    • HEK-293 Cells
    • Cell-free protein synthesis (CFPS)
    • Wheat germ
  • 抗原表位
    • AA 1-128
    • AA 1-126
    • AA 1-127
    • AA 18-115
    • Transcript Variant 1
  • 标记
    • His tag
    • Strep Tag
    • 非结合性
    • GST tag
    • Myc-DYKDDDDK Tag
  • 蛋白类型
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
    • Frozen
  • 生物活性
    • Biologically Active
  • Grade
    • custom-made
  • Supplier
    • antibodies-online
    • CUSABIO
    • Abbexa
    • OriGene

Aliases for SH2D1A 蛋白

SH2 domain containing 1A (SH2D1A) 蛋白
SH2 domain containing 1A (Sh2d1a) 蛋白
DSHP 蛋白
EBVS 蛋白
Gm686 蛋白
IMD5 蛋白
LYP 蛋白
MTCP1 蛋白
RGD1562408 蛋白
SAP 蛋白
SAP/SH2D1A 蛋白
SH2D1A 蛋白
XLP 蛋白
XLPD 蛋白
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