This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer. [provided by RefSeq, Jul 2008].
Merino, Singla: "Secreted Frizzled-Related Protein-2 Inhibits Doxorubicin-Induced Apoptosis Mediated through the Akt-mTOR Pathway in Soleus Muscle." in: Oxidative medicine and cellular longevity, Vol. 2018, pp. 6043064, (2018) (PubMed).
Aliases for SFRP2 蛋白
secreted frizzled-related protein 2 (sfrp2) 蛋白 secreted frizzled related protein 2 (SFRP2) 蛋白 secreted frizzled-related protein 2 S homeolog (sfrp2.S) 蛋白 secreted frizzled-related protein (sfrp2) 蛋白 sfrp2 (LOAG_01461) 蛋白 secreted frizzled-related protein 2 (Sfrp2) 蛋白 AI851596 蛋白 frp-2 蛋白 FRP-2 蛋白 hm:zeh0225 蛋白 sarp1 蛋白 SARP1 蛋白 sdf-5 蛋白 SDF-5 蛋白 Sdf5 蛋白 sfrp-2 蛋白 SFRP-2 蛋白 SFRP2 蛋白 sfrp2 蛋白 zeh0225 蛋白 zgc:153618 蛋白