蛋白简介

This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).

Alternative names and synonyms associated with Hexosaminidase A (HEXA)

• hexosaminidase subunit alpha (HEXA) 抗体
• hexosaminidase B (beta polypeptide) (hexb) 抗体
• CUGBP Elav-like family member 6 (CELF6) 抗体
• hexosaminidase A (Hexa) 抗体
• hexosaminidase subunit alpha (Hexa) 抗体
• 显示所有的基因名称
• hexosaminidase A (alpha polypeptide) (hexa) 抗体
• beta-hexosaminidase subunit alpha-like (LOC100228061) 抗体

• fc04h11 抗体
• Hex-1 抗体
• HEXA 抗体
• si:dkey-35i22.2 抗体
• TSD 抗体
• 显示所有的同义词和别名
• wu:fc04h11 抗体
• wu:fv09f06 抗体
• zgc:112084 抗体

Protein level used designations for Hexosaminidase A (HEXA) ELISA试剂盒

N-acetyl-beta-glucosaminidase subunit alpha , beta-N-acetylhexosaminidase subunit alpha , beta-hexosaminidase subunit alpha , hexosaminidase subunit A , beta-hexosaminidase subunit beta , beta-hexosaminidase alpha chain , hexosaminidase A (alpha polypeptide) , beta-hexosaminidase alpha-subunit , hexosaminidase A alpha , Hexose aminidase A (alpha polypeptide) , hexosaminidase A , Beta-hexosaminidase alpha chain