Recombinant 小鼠 anti-人 IgA (full length), (Heavy Chain) Antibody
Carrier-free
IHC (p)
Monoclonal
rHISA43
IgG1
Recombinant Antibody
unconjugated
产品编号 ABIN7879397
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Recombinant 小鼠 anti-人 IgA (full length), (Heavy Chain) Antibody (ABIN7879397)
抗原
IgA
抗体类型
Recombinant Antibody
克隆类型
单克隆
应用范围
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
质量等级
Carrier-free
克隆位点
RHISA43
亚型
IgG1, kappa
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抗原表位
- full length, Heavy Chain
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适用
- 人
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宿主
- 小鼠
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原理
- Recombinant IgA Heavy Chain Antibody (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- Full length recombinant human IGHA protein was used as the immunogen for the human recombinant IgA Heavy Chain antibody.
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Mouse anti-Human IgA antibody
ELISA, IHC (p) Monoclonal AD2-947 IgG1 unconjugated
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应用备注
- Optimal dilution of the recombinant IgA Heavy Chain antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the recombinant IgA Heavy Chain antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- IgA
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物质类
- Antibody
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背景
- This MAb is specific to heavy chain of IgA and shows minimal cross-reaction with heavy chains of other immunoglobulins. It is reactive with all subclasses of Alpha heavy chain. Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through inter-chain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin A (IgA) is the main protein of the mucosal immune system. It is generated by B-cells in gut-associated lymphoid tissues. Daily production of IgA exceeds that of any of the other immunoglobulins.IgA exists mainly in dimers but can also exist as polymers or as monomers. Dimers and polymers contain a joining (J) chain that can be bound by the polymeric immunoglobulin receptor (pIgR) for transportation of the molecule to mucosal surfaces. The most common feature of plasmacytomas, and certain non-Hodgkins lymphomas is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
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UniProt
- P01876
抗原
-
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