小鼠 anti-人 IgD (full length) Antibody
Carrier-free
IHC (p)
Monoclonal
IgD26
IgG1
unconjugated
产品编号 ABIN7878395
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for 小鼠 anti-人 IgD (full length) Antibody (ABIN7878395)
抗原
IgD
克隆类型
单克隆
应用范围
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
质量等级
Carrier-free
克隆位点
IgD26
亚型
IgG1, kappa
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抗原表位
- full length
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适用
- 人
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宿主
- 小鼠
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原理
- Human IgD Antibody / Heavy chain (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- Full length recombinant human IGHD protein was used as the immunogen for the human IgD antibody.
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应用备注
- Optimal dilution of the human IgD antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the human IgD antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- IgD
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物质类
- Antibody
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背景
- Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through interchain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin D (IgD) exists as a monomer with light chains. It plays a biological role as a transmembrane receptor molecule, co-expressed with IgM on the surface of mature/naive B cells. In particular, it is found on spleen B cell surfaces. Compared to IgM, IgD exists in much lower numbers and is not expressed on immature B cells. IgD surface expression on B cells is regulated in part by IL-27. In mice, the inhibition of this immunoglobulin isotype does not cause a significant change to the immune system.
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UniProt
- P01880
抗原
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