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Recombinant 兔 anti-人 IgD (AA 1-200) Antibody

Carrier-free IHC (p) Monoclonal IGHD-8326R IgG Recombinant Antibody unconjugated
产品编号 ABIN7868564
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant 兔 anti-人 IgD (AA 1-200) Antibody (ABIN7868564)

抗原

IgD

抗体类型

Recombinant Antibody

克隆类型

  • 44
  • 33
单克隆

应用范围

  • 31
  • 29
  • 16
  • 14
  • 13
  • 11
  • 9
  • 7
  • 7
  • 4
  • 3
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

IGHD-8326R

亚型

IgG, kappa
  • 抗原表位

    • 17
    • 7
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    AA 1-200

    适用

    • 55
    • 17
    • 6

    宿主

    • 24
    • 19
    • 19
    • 11
    • 5

    原理

    IgD Antibody / Heavy chain (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the IgD antibody.
  • 应用备注

    Optimal dilution of the IgD antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the IgD antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    IgD

    物质类

    Antibody

    背景

    Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through interchain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin D (IgD) exists as a monomer with delta heavy chains and either kappa or lambda light chains. It plays a biological role as a transmembrane receptor molecule, co-expressed with IgM on the surface of mature/naive B cells. In particular, it is found on spleen B cell surfaces. Compared to IgM, IgD exists in much lower numbers and is not expressed on immature B cells. IgD surface expression on B cells is regulated in part by IL-27. In mice, the inhibition of this immunoglobulin isotype does not cause a significant change to the immune system.

    UniProt

    P01880
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