Recombinant 兔 anti-人 IgD (AA 1-200) Antibody
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Quick Overview for Recombinant 兔 anti-人 IgD (AA 1-200) Antibody (ABIN7868564)
抗原
抗体类型
克隆类型
应用范围
质量等级
克隆位点
亚型
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抗原表位
- AA 1-200
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适用
- 人
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宿主
- 兔
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原理
- IgD Antibody / Heavy chain (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the IgD antibody.
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应用备注
- Optimal dilution of the IgD antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the IgD antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- IgD
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物质类
- Antibody
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背景
- Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through interchain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin D (IgD) exists as a monomer with delta heavy chains and either kappa or lambda light chains. It plays a biological role as a transmembrane receptor molecule, co-expressed with IgM on the surface of mature/naive B cells. In particular, it is found on spleen B cell surfaces. Compared to IgM, IgD exists in much lower numbers and is not expressed on immature B cells. IgD surface expression on B cells is regulated in part by IL-27. In mice, the inhibition of this immunoglobulin isotype does not cause a significant change to the immune system.
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UniProt
- P01880
抗原
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