SERPINA1 蛋白
(serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1))
The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
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36 results :
SERPINA1
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
Greater than 95 % by SDS-PAGE gel analyses
WB, ELISA
1 image
SERPINA1
宿主: 小鼠
宿主: 人细胞
Recombinant
> 95 % as determined by reducing SDS-PAGE.
1 image
SERPINA1
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
1 reference
SERPINA1
宿主: 大鼠
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
SERPINA1
宿主: 人
宿主: 人细胞
Recombinant
> 95 % as determined by reducing SDS-PAGE.
SERPINA1
宿主: 大鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
WB, SDS, Imm, PC
SERPINA1
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
WB, SDS, Imm, PC
SERPINA1
宿主: 小鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 %
WB, SDS, Imm, PC
SERPINA1
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 97 % as determined by reducing SDS-PAGE.
Active
SERPINA1
宿主: 人
宿主: 人细胞
Recombinant
> 95 % as determined by reducing SDS-PAGE.
SERPINA1
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
SERPINA1
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
SERPINA1
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
SERPINA1
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
SERPINA1
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
SERPINA1
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
SERPINA1
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Latest Publications for our SERPINA1 蛋白
: "Survival Advantage of Both Human Hepatocyte Xenografts and Genome-Edited Hepatocytes for Treatment of α-1 Antitrypsin Deficiency." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 25, Issue 11, pp. 2477-2489, (2017) (PubMed).: "Erratum to: Rectocutaneous fistula with transmigration of the suture: a rare delayed complication of vault fixation with the sacrospinous ligament." in: International urogynecology journal, Vol. 27, Issue 3, pp. 505, (2016) (PubMed).
: "LaCyTools: A Targeted Liquid Chromatography-Mass Spectrometry Data Processing Package for Relative Quantitation of Glycopeptides." in: Journal of proteome research, Vol. 15, Issue 7, pp. 2198-210, (2016) (PubMed).
: "Alpha-1 Antitrypsin Mitigates the Inhibition of Airway Epithelial Cell Repair by Neutrophil Elastase." in: American journal of respiratory cell and molecular biology, Vol. 54, Issue 3, pp. 341-9, (2016) (PubMed).
: "Serine Protease Activation Essential for Endothelial-Mesenchymal Transition in Vascular Calcification." in: Circulation research, Vol. 117, Issue 9, pp. 758-69, (2015) (PubMed).
: "The BLT1 Inhibitory Function of ?-1 Antitrypsin Augmentation Therapy Disrupts Leukotriene B4 Neutrophil Signaling." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 8, pp. 3628-41, (2015) (PubMed).
: "Enhanced recognition of plasma proteins in a non-native state by complement C3b. A possible clearance mechanism for damaged proteins in blood." in: Molecular immunology, Vol. 64, Issue 1, pp. 55-62, (2015) (PubMed).
: "Progranulin is a substrate for neutrophil-elastase and proteinase-3 in the airway and its concentration correlates with mediators of airway inflammation in COPD." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 306, Issue 1, pp. L80-7, (2014) (PubMed).
: "Generation of multiple fluid-phase C3b:plasma protein complexes during complement activation: possible implications in C3 glomerulopathies." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 3, pp. 1220-30, (2014) (PubMed).
Aliases for SERPINA1 蛋白
serpin family A member 3 (SERPINA3) 蛋白alpha-1-antiproteinase F precursor (LOC100008973) 蛋白
serpin family A member 1 (SERPINA1) 蛋白
alpha-1-antitrypsin (LOC100328621) 蛋白
calumenin (CALU) 蛋白
serpin family A member 1 (Serpina1) 蛋白
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 S homeolog (serpina1.S) 蛋白
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (serpina1) 蛋白
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 (SPIA5) 蛋白
SH2B adaptor protein 2 (Sh2b2) 蛋白
calumenin (Calu) 蛋白
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (Serpina1) 蛋白
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 (SERPINA3) 蛋白
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 L homeolog (serpina1.L) 蛋白
A1A 蛋白
A1AT 蛋白
AACT 蛋白
AAT 蛋白
ACT 蛋白
alpha-1-PI 蛋白
alpha1AT 蛋白
Aps 蛋白
GIG25 蛋白
MGC64429 蛋白
PI 蛋白
Pi 蛋白
PI1 蛋白
PRO2275 蛋白
serpina1d 蛋白
SERPINA3-5 蛋白
Spi1 蛋白
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