SEMA4D/CD100 抗体
(Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))
Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system\; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA (By similarity).
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Latest Publications for our SEMA4D/CD100 抗体
: "Sema4D/PlexinB1 inhibition ameliorates blood-brain barrier damage and improves outcome after stroke in rats." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 32, Issue 4, pp. 2181-2196, (2018) (PubMed).: "Interferon-α-induced CD100 on naïve CD8+ T cells enhances antiviral responses to hepatitis C infection through CD72 signal transduction." in: The Journal of international medical research, Vol. 45, Issue 1, pp. 89-100, (2017) (PubMed).
: "CD100 up-regulation induced by interferon-α on B cells is related to hepatitis C virus infection." in: PLoS ONE, Vol. 9, Issue 12, pp. e113338, (2014) (PubMed).
: "Phage display identification of CD100 in human atherosclerotic plaque macrophages and foam cells." in: PLoS ONE, Vol. 8, Issue 9, pp. e75772, (2013) (PubMed).
: "CD100 on NK cells enhance IFNgamma secretion and killing of target cells expressing CD72." in: PLoS ONE, Vol. 2, Issue 9, pp. e818, (2007) (PubMed).
: "Caspases disrupt the nuclear-cytoplasmic barrier." in: The Journal of cell biology, Vol. 151, Issue 5, pp. 951-9, (2000) (PubMed).
: "Human CD100, a novel leukocyte semaphorin that promotes B-cell aggregation and differentiation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 21, pp. 11780-5, (1996) (PubMed).
: "Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line." in: Molecular and cellular biology, Vol. 10, Issue 4, pp. 1793-8, (1990) (PubMed).
Aliases for SEMA4D/CD100 抗体
semaphorin 4D (Sema4d) 抗体semaphorin 4D (SEMA4D) 抗体
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D (Sema4d) 抗体
C9orf164 抗体
CD100 抗体
coll-4 抗体
COLL-4 抗体
M-sema-G 抗体
Semacl2 抗体
SEMAJ 抗体
Semaj 抗体
Semcl2 抗体
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