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SCN1A 抗体

(Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A))
The vertebrate sodium channel is a voltage-gated ion channel essential for the generation and propagation of action potentials, mainly in nerve and muscle. Voltage-sensitive sodium channels are heteromeric complexes consisting of a large central pore-forming glycosylated alpha subunit, and two smaller auxiliary beta subunits. This gene encodes the large alpha subunit, and mutations in this gene have been associated with several epilepsy, convulsion and migraine disorders. Alternative splicing results in multiple transcript variants. The RefSeq Project has decided to create four representative RefSeq records. Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons, the exact combination of which have not been experimentally confirmed for the full-length transcript.[provided by RefSeq, Jan 2011].

37 results

KO Validated SCN1A 适用: 大鼠 IHC, IF 宿主: 兔 Polyclonal Atto 594
产品编号 ABIN7043639
 
SCN1A 适用: 大鼠 IHC, ELISA, WB, ICC, IP 宿主: 小鼠 Monoclonal K74-71 unconjugated
产品编号 ABIN7595940
 
SCN1A 适用: 人, 大鼠 宿主: 兔 Polyclonal Alexa Fluor 680
产品编号 ABIN6908188
 
SCN1A 适用: 人, 大鼠 宿主: 兔 Polyclonal Biotin
产品编号 ABIN6876062
 
SCN1A 适用: 人, 大鼠 宿主: 兔 Polyclonal Alexa Fluor 555
产品编号 ABIN6892125
 
SCN1A 适用: 人, 大鼠 宿主: 兔 Polyclonal Alexa Fluor 647
产品编号 ABIN6918739
 
SCN1A 适用: 人, 大鼠 宿主: 兔 Polyclonal Alexa Fluor 488
产品编号 ABIN6819746
 
SCN1A 适用: 人, 大鼠 宿主: 兔 Polyclonal Alexa Fluor 750
产品编号 ABIN6859999
 
SCN1A 适用: 人, 大鼠 宿主: 兔 Polyclonal Alexa Fluor 594
产品编号 ABIN6835809
 
SCN1A 适用: 大鼠 IHC, ELISA, WB, ICC, IP 宿主: 小鼠 Monoclonal K74-71 unconjugated
产品编号 ABIN1304838
 
SCN1A 适用: 大鼠 IHC, ELISA, WB, ICC, IP 宿主: 小鸡, 小鼠 Chimeric K74-71 unconjugated Recombinant Antibody
产品编号 ABIN7607146
 
SCN1A 适用: 大鼠 IHC, ICC 宿主: 小鼠 Monoclonal K74-71 FL550
产品编号 ABIN7595617
 
SCN1A 适用: 大鼠 IHC, ICC 宿主: 小鼠 Monoclonal K74-71 FL490
产品编号 ABIN7595485
 
SCN1A 适用: 大鼠 IHC, ICC 宿主: 小鼠 Monoclonal K74-71 FL594
产品编号 ABIN7595749
 
SCN1A 适用: 大鼠 IHC, ICC 宿主: 小鼠 Monoclonal K74-71 FL650
产品编号 ABIN7595881
 
SCN1A 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2765873
 
SCN1A 适用: 小鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7581955
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • Immunohistochemistry (IHC)
    • ELISA
    • Immunocytochemistry (ICC)
    • Immunoprecipitation (IP)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunofluorescence (IF)
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
    • Enzyme Immunoassay (EIA)
    • Flow Cytometry (FACS)
    • Fluorescence Microscopy (FM)
    • Immunochromatography (IC)
    • Immunofluorescence (Cultured Cells) (IF (cc))
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 适用
    • Rat
    • Human
    • Mouse
  • 图像
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
    • Chicken
    • Guinea Pig
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
    • Chimeric
  • 克隆
    • K74-71
    • 6H2
    • K74-53
    • RB57630
    • S74-71
  • 抗原表位
    • AA 1929-2009
    • AA 992-1099
    • AA 465-481
    • Intracellular
    • C-Term
    • N-Term
    • AA 1901-2009
    • AA 1981-2009
    • AA 274-399
    • AA 311-324
    • AA 33-82
    • AA 481-515
    • Extracellular
    • Internal Region
  • 标记
    • 非结合性
    • Biotin
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
    • Atto 594
    • FITC
    • FL490
    • FL550
    • FL594
    • FL650
    • HRP
  • 抗体亚型
    • IgG
    • IgG1
    • IgG2a
    • kappa
    • Ig Fraction
    • IgY
  • 蛋白类型
    • Recombinant Antibody
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • KO Validated
  • Supplier
    • antibodies-online
    • Antibodies Incorporated
    • Signalway
    • Alomone Labs
    • Acris
    • Boster Bio
    • Covalab
    • RayBiotech
    • Rockland

Latest Publications for our SCN1A 抗体

Wimmer, Harty, Richards, Phillips, Miyazaki, Nukina, Petrou: "Sodium channel β1 subunit localizes to axon initial segments of excitatory and inhibitory neurons and shows regional heterogeneity in mouse brain." in: The Journal of comparative neurology, Vol. 523, Issue 5, pp. 814-30, (2015) (PubMed).

Freeman, Desmazières, Simonnet, Gatta, Pfeiffer, Aigrot, Rappeneau, Guerreiro, Michel, Yanagawa, Barbin, Brophy, Fricker, Lubetzki, Sol-Foulon: "Acceleration of conduction velocity linked to clustering of nodal components precedes myelination." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 3, pp. E321-8, (2015) (PubMed).

Tian, Wang, Ke, Guo, Shu: "Molecular identity of axonal sodium channels in human cortical pyramidal cells." in: Frontiers in cellular neuroscience, Vol. 8, pp. 297, (2014) (PubMed).

Li, Tian, Scalmani, Frassoni, Mantegazza, Wang, Yang, Wu, Shu: "Action potential initiation in neocortical inhibitory interneurons." in: PLoS biology, Vol. 12, Issue 9, pp. e1001944, (2014) (PubMed).

Papale, Makinson, Christopher Ehlen, Tufik, Decker, Paul, Escayg: "Altered sleep regulation in a mouse model of SCN1A-derived genetic epilepsy with febrile seizures plus (GEFS+)." in: Epilepsia, Vol. 54, Issue 4, pp. 625-34, (2013) (PubMed).

Xiao, Bosch, Nerbonne, Ornitz: "FGF14 localization and organization of the axon initial segment." in: Molecular and cellular neurosciences, Vol. 56, pp. 393-403, (2013) (PubMed).

Vega, Avila, Matthews: "Interaction between the transcriptional corepressor Sin3B and voltage-gated sodium channels modulates functional channel expression." in: Scientific reports, Vol. 3, pp. 2809, (2013) (PubMed).

Puthussery, Venkataramani, Gayet-Primo, Smith, Taylor: "NaV1.1 channels in axon initial segments of bipolar cells augment input to magnocellular visual pathways in the primate retina." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 41, pp. 16045-59, (2013) (PubMed).

Wykes, Kalmbach, Eliava, Waters: "Changes in the physiology of CA1 hippocampal pyramidal neurons in preplaque CRND8 mice." in: Neurobiology of aging, Vol. 33, Issue 8, pp. 1609-23, (2012) (PubMed).

Kim, Gersbacher, Inquimbert, Kovacs: "Reduced sodium channel Na(v)1.1 levels in BACE1-null mice." in: The Journal of biological chemistry, Vol. 286, Issue 10, pp. 8106-16, (2011) (PubMed).

Aliases for SCN1A 抗体

sodium voltage-gated channel alpha subunit 1 (SCN1A) 抗体
sodium voltage-gated channel alpha subunit 9 (SCN9A) 抗体
sodium channel, voltage-gated, type I, alpha (Scn1a) 抗体
sodium voltage-gated channel alpha subunit 1 (Scn1a) 抗体
B230332M13 抗体
EIEE6 抗体
FEB3 抗体
FEB3A 抗体
FHM3 抗体
GEFSP2 抗体
HBSCI 抗体
NAC1 抗体
Nav1.1 抗体
SCN1 抗体
SCN1A 抗体
SCN9A 抗体
SMEI 抗体
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