Sclerostin 抗体
(Sclerostin (SOST))
Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| Sclerostin 抗体 | 人 | 兔 Polyclonal |
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| Sclerostin 抗体 (AbBy Fluor® 594) | 人 | 兔 Polyclonal |
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| Sclerostin 抗体 (AbBy Fluor® 350) | 人 | 兔 Polyclonal |
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| Sclerostin 抗体 (Cy5) | 人 | 兔 Polyclonal |
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| Sclerostin 抗体 (AA 121-180) (AbBy Fluor® 350) | 人 | 兔 Polyclonal |
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| Sclerostin 抗体 (AA 121-180) (AbBy Fluor® 594) | 人 | 兔 Polyclonal |
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| Sclerostin 抗体 (AA 121-180) (AbBy Fluor® 555) | 人 | 兔 Polyclonal |
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| Sclerostin 抗体 (AA 121-180) (AbBy Fluor® 488) | 人 | 兔 Polyclonal |
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| Sclerostin 抗体 (AA 121-180) (AbBy Fluor® 680) | 人 | 兔 Polyclonal |
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| Sclerostin 抗体 (AA 121-180) (AbBy Fluor® 750) | 人 | 兔 Polyclonal |
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| Sclerostin 抗体 (AA 121-180) (Cy5) | 人 | 兔 Polyclonal |
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| Sclerostin 抗体 (AA 121-180) (Cy5.5) | 人 | 兔 Polyclonal |
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| Sclerostin 抗体 (AA 121-180) (Cy7) | 人 | 兔 Polyclonal |
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| Sclerostin 抗体 (AA 121-180) (Biotin) | 人 | 兔 Polyclonal |
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| Sclerostin 抗体 (AA 121-180) (AbBy Fluor® 647) | 人 | 兔 Polyclonal |
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| Sclerostin 抗体 (AA 121-180) (Cy3) | 人 | 兔 Polyclonal |
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| Sclerostin 抗体 (AA 121-180) (FITC) | 人 | 兔 Polyclonal |
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| Sclerostin 抗体 (AA 121-180) (HRP) | 人 | 兔 Polyclonal |
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| Sclerostin 抗体 (AA 131-211) (HRP) | 小鼠 | 兔 Polyclonal |
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| Sclerostin 抗体 (AA 131-211) | 小鼠 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IF (Immunofluorescence: 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 594
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 350
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy5
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 350
- 抗体亚型
- IgG
- 抗原表位
- AA 121-180
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 594
- 抗体亚型
- IgG
- 抗原表位
- AA 121-180
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 555
- 抗体亚型
- IgG
- 抗原表位
- AA 121-180
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 488
- 抗体亚型
- IgG
- 抗原表位
- AA 121-180
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 680
- 抗体亚型
- IgG
- 抗原表位
- AA 121-180
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 750
- 抗体亚型
- IgG
- 抗原表位
- AA 121-180
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy5
- 抗体亚型
- IgG
- 抗原表位
- AA 121-180
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy5.5
- 抗体亚型
- IgG
- 抗原表位
- AA 121-180
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy7
- 抗体亚型
- IgG
- 抗原表位
- AA 121-180
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 121-180
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 647
- 抗体亚型
- IgG
- 抗原表位
- AA 121-180
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy3
- 抗体亚型
- IgG
- 抗原表位
- AA 121-180
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 121-180
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- AA 121-180
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- AA 131-211
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 131-211
Latest Publications for our Sclerostin 抗体
: "Vascularized in vitro bone model as 3D quadruple culture with primary human osteoblasts, osteocytes, osteoclasts and endothelial cells." in: Materials today. Bio, Vol. 34, pp. 102154, (2025) (PubMed).
: "Targeting SOST using a small-molecule compound retards breast cancer bone metastasis." in: Molecular cancer, Vol. 21, Issue 1, pp. 228, (2023) (PubMed).
: "Co-expression of DKK-1 and Sclerostin in Subchondral Bone of the Proximal Femoral Heads from Osteoarthritic Hips." in: Calcified tissue international, Vol. 100, Issue 6, pp. 609-618, (2018) (PubMed).
: "Protection From Glucocorticoid-Induced Osteoporosis by Anti-Catabolic Signaling in the Absence of Sost/Sclerostin." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 31, Issue 10, pp. 1791-1802, (2016) (PubMed).
: "Single-pulsed electromagnetic field therapy increases osteogenic differentiation through Wnt signaling pathway and sclerostin downregulation." in: Bioelectromagnetics, Vol. 36, Issue 7, pp. 494-505, (2015) (PubMed).
: "Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 21, Issue 11, pp. 1738-49, (2006) (PubMed).
: "LRP5 mutations linked to high bone mass diseases cause reduced LRP5 binding and inhibition by SOST." in: The Journal of biological chemistry, Vol. 281, Issue 50, pp. 38276-84, (2006) (PubMed).
: "Human genetics of SOST." in: Journal of musculoskeletal & neuronal interactions, Vol. 6, Issue 4, pp. 355-6, (2006) (PubMed).
: "Targeting SOST using a small-molecule compound retards breast cancer bone metastasis." in: Molecular cancer, Vol. 21, Issue 1, pp. 228, (2023) (PubMed).
: "Co-expression of DKK-1 and Sclerostin in Subchondral Bone of the Proximal Femoral Heads from Osteoarthritic Hips." in: Calcified tissue international, Vol. 100, Issue 6, pp. 609-618, (2018) (PubMed).
: "Protection From Glucocorticoid-Induced Osteoporosis by Anti-Catabolic Signaling in the Absence of Sost/Sclerostin." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 31, Issue 10, pp. 1791-1802, (2016) (PubMed).
: "Single-pulsed electromagnetic field therapy increases osteogenic differentiation through Wnt signaling pathway and sclerostin downregulation." in: Bioelectromagnetics, Vol. 36, Issue 7, pp. 494-505, (2015) (PubMed).
: "Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 21, Issue 11, pp. 1738-49, (2006) (PubMed).
: "LRP5 mutations linked to high bone mass diseases cause reduced LRP5 binding and inhibition by SOST." in: The Journal of biological chemistry, Vol. 281, Issue 50, pp. 38276-84, (2006) (PubMed).
: "Human genetics of SOST." in: Journal of musculoskeletal & neuronal interactions, Vol. 6, Issue 4, pp. 355-6, (2006) (PubMed).
Aliases for Sclerostin 抗体
sclerostin (LOC100313724) 抗体sclerostin (SOST) 抗体
sclerostin (Sost) 抗体
5430411E23Rik 抗体
CDD 抗体
LOC100313724 抗体
VBCH 抗体
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