SARS-CoV-2 Spike S1 抗体
(SARS-CoV-2 Spike S1)
attaches the virion to the cell membrane by interacting with host receptor, initiating the infection (By similarity). Binding to human ACE2 receptor and internalization of the virus into the endosomes of the host cell induces conformational changes in the Spike glycoprotein (PubMed:32142651, PubMed:32075877, PubMed:32155444). Uses also human TMPRSS2 for priming in human lung cells which is an essential step for viral entry (PubMed:32142651). Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes.
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47 results
适用: SARS Coronavirus-2 (SARS-CoV-2), SARS Coronavirus (SARS-CoV), SARS CoV-2 Alpha, SARS CoV-2 Beta, SARS CoV-2 Epsilon, SARS CoV-2 Gamma, SARS CoV-2 Eta, SARS CoV-2 Kappa, SARS CoV-2 Delta, SARS CoV-2 Omicron
ELISA, IF, Crys, SPR
宿主: Human
Monoclonal
CR3022
unconjugated
Recombinant Antibody
8 references
1 validation
Independently Validated
适用: SARS Coronavirus-2 (SARS-CoV-2), SARS Coronavirus (SARS-CoV), SARS CoV-2 Alpha, SARS CoV-2 Beta, SARS CoV-2 Epsilon, SARS CoV-2 Gamma, SARS CoV-2 Eta, SARS CoV-2 Kappa
ELISA, IF, Crys, SPR
宿主: 兔
Chimeric
CR3022
unconjugated
Recombinant Antibody
5 references
适用: SARS Coronavirus-2 (SARS-CoV-2)
ELISA, GICA, Neut
宿主: Human
Monoclonal
A1
unconjugated
single-domain Antibody (sdAb)
Recombinant Antibody
适用: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Alpha, SARS CoV-2 Beta, SARS CoV-2 Epsilon, SARS CoV-2 Gamma
ELISA, Neut
宿主: Human
Chimeric
AM122
unconjugated
适用: SARS Coronavirus-2 (SARS-CoV-2)
ELISA, GICA
宿主: Human
Chimeric
H6
unconjugated
Recombinant Antibody
适用: SARS Coronavirus-2 (SARS-CoV-2)
ELISA
宿主: 兔
Polyclonal
unconjugated
1 reference
适用: SARS Coronavirus-2 (SARS-CoV-2)
ELISA
宿主: Human
Monoclonal
H6
Biotin
scFv fragment
Recombinant Antibody
1 image
适用: SARS Coronavirus-2 (SARS-CoV-2)
ELISA
宿主: Human
Monoclonal
H6
HRP
scFv fragment
Recombinant Antibody
1 image
适用: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Alpha
ELISA, IHC
宿主: 兔
Monoclonal
SP185
unconjugated
1 image
适用: SARS Coronavirus-2 (SARS-CoV-2), SARS Coronavirus (SARS-CoV)
ELISA, IF, Crys, SPR
宿主: Human
Monoclonal
CR3022
unconjugated
Recombinant Antibody
1 image
适用: SARS Coronavirus-2 (SARS-CoV-2), SARS Coronavirus (SARS-CoV)
ELISA, IF, Crys, SPR
宿主: Human
Monoclonal
CR3022
unconjugated
Recombinant Antibody
1 image
适用: SARS Coronavirus-2 (SARS-CoV-2)
ELISA, WB, LF
宿主: Cell culture
Monoclonal
unconjugated
1 image
适用: SARS Coronavirus-2 (SARS-CoV-2)
ELISA
宿主: Camelid (Camelidae)
Monoclonal
Sb23
unconjugated
single-domain Antibody (sdAb)
Recombinant Antibody
适用: SARS Coronavirus-2 (SARS-CoV-2)
ELISA, IF
宿主: 兔
Monoclonal
R007
unconjugated
适用: SARS Coronavirus-2 (SARS-CoV-2)
ELISA
宿主: Human
Monoclonal
H6
FITC
scFv fragment
Recombinant Antibody
适用: SARS Coronavirus-2 (SARS-CoV-2)
ELISA, GICA
宿主: HEK-293 Cells
Chimeric
H6
Fc Tag
scFv fragment
Recombinant Antibody
适用: SARS Coronavirus-2 (SARS-CoV-2)
ELISA, WB
宿主: 小鼠
Monoclonal
2A6
unconjugated
适用: SARS Coronavirus-2 (SARS-CoV-2)
ELISA
宿主: 兔
Polyclonal
Biotin
适用: SARS Coronavirus-2 (SARS-CoV-2)
ELISA, WB, IF, IHC
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our SARS-CoV-2 Spike S1 抗体
: "Antibody course and memory B-cell response in the first year after SARS-CoV-2 infection." in: The Journal of infectious diseases, (2022) (PubMed).: "Highly shape- and size-tunable membrane nanopores made with DNA." in: Nature nanotechnology, (2022) (PubMed).
: "Microfluidic particle dam for direct visualization of SARS-CoV-2 antibody levels in COVID-19 vaccinees." in: Science advances, Vol. 8, Issue 22, pp. eabn6064, (2022) (PubMed).
: "High antibody levels and reduced cellular response in children up to one year after SARS-CoV-2 infection. ..." in: Nature communications, Vol. 13, Issue 1, pp. 7315, (2022) (PubMed).
: "Dromedary camels as a natural source of neutralizing nanobodies against SARS-CoV-2." in: JCI insight, (2021) (PubMed).
: "Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 S for viral entry. ..." in: Molecular therapy : the journal of the American Society of Gene Therapy, (2021) (PubMed).
: "Rapid seroconversion and persistent functional IgG antibodies in severe COVID-19 patients correlates with an IL-12p70 and IL-33 signature." in: Scientific reports, Vol. 11, Issue 1, pp. 3461, (2021) (PubMed).
: "Development and performance characteristics evaluation of a new Bioelectric Recognition Assay (BERA) method for rapid Sars-CoV-2 detection in clinical samples." in: Journal of virological methods, Vol. 293, pp. 114166, (2021) (PubMed).
: "Safe and effective two-in-one replicon-and-VLP minispike vaccine for COVID-19: Protection of mice after a single immunization." in: PLoS pathogens, Vol. 17, Issue 4, pp. e1009064, (2021) (PubMed).
: "Implementing a method for engineering multivalency to substantially enhance binding of clinical trial anti-SARS-CoV-2 antibodies to wildtype spike and variants of concern proteins." in: Scientific reports, Vol. 11, Issue 1, pp. 10475, (2021) (PubMed).
Aliases for SARS-CoV-2 Spike S1 抗体
Surface Glycoprotein (S) 抗体E2 抗体
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