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SARS-CoV-2 Spike 蛋白

(SARS-CoV-2 Spike (SARS-CoV-2 S))
mediates fusion of the virion and cellular membranes by acting as a class I viral fusion protein. Under the current model, the protein has at least three conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.

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  • 抗原: SARS-CoV-2 Spike (SARS-CoV-2 S)
  • Protein
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN7669621
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, K378R, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • 100 μg
发货至: 中国
ABIN7669650
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD) (rFc Tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • 100 μg
发货至: 中国
ABIN7669651
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD) (rFc Tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • 100 μg
发货至: 中国
ABIN7669653
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD) (rFc Tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • 100 μg
发货至: 中国
ABIN7669690
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD, V367F) (mFc Tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • 100 μg
发货至: 中国
ABIN7580947
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD) (Fc Tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) Mammalian Cells
  • ELISA (ELISA: 所列应用)
  • SDS (SDS-PAGE: 所列应用)
  • WB (Western Blotting: 所列应用)
  • 100 μg
发货至: 中国
ABIN7669628
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • 100 μg
发货至: 中国
ABIN7669580
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD) (mFc Tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • 100 μg
发货至: 中国
ABIN7669682
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD, W436R) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • ELISA (ELISA: 所列应用)
  • 100 μg
发货至: 中国
ABIN7669656
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • 20 μg
发货至: 中国
ABIN7580930
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, N440K, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) Mammalian Cells
  • ELISA (ELISA: 所列应用)
  • SDS (SDS-PAGE: 所列应用)
  • WB (Western Blotting: 所列应用)
  • 100 μg
发货至: 中国
ABIN7890306
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, F342L, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) 人细胞
  • 1 mg
发货至: 中国
ABIN7669630
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • 100 μg
发货至: 中国
ABIN7890311
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, K458R, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) 人细胞
  • 1 mg
发货至: 中国
ABIN7890310
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (A435S, AA 319-541, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) 人细胞
  • 1 mg
发货至: 中国
ABIN7580944
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD, V367F) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) Mammalian Cells
  • ELISA (ELISA: 所列应用)
  • SDS (SDS-PAGE: 所列应用)
  • WB (Western Blotting: 所列应用)
  • 100 μg
发货至: 中国
ABIN7669667
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • ELISA (ELISA: 所列应用)
  • 100 μg
发货至: 中国
ABIN7580950
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) Insect Cells
  • ELISA (ELISA: 所列应用)
  • SDS (SDS-PAGE: 所列应用)
  • WB (Western Blotting: 所列应用)
  • 100 μg
发货至: 中国
ABIN7669649
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • ELISA (ELISA: 所列应用)
  • 100 μg
发货至: 中国
ABIN7669657
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • ELISA (ELISA: 所列应用)
  • 100 μg
发货至: 中国
Protein
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 85 % as determined by reducing SDS-PAGE.
产品编号 ABIN7669621
Protein
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7669650
Protein
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7669651
Protein
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7669653
Protein
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 90 % as determined by reducing SDS-PAGE.
产品编号 ABIN7669690
Protein
  • ELISA (ELISA: 所列应用)
  • SDS (SDS-PAGE: 所列应用)
  • WB (Western Blotting: 所列应用)
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
Mammalian Cells
蛋白类型
Recombinant
纯度
>90 % as determined by SDS-PAGE.
产品编号 ABIN7580947
Protein
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7669628
Protein
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7669580
Protein
  • ELISA (ELISA: 所列应用)
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 95 % as determined by reducing SDS-PAGE.
生物活性
Active
产品编号 ABIN7669682
Protein
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7669656
Protein
  • ELISA (ELISA: 所列应用)
  • SDS (SDS-PAGE: 所列应用)
  • WB (Western Blotting: 所列应用)
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
Mammalian Cells
蛋白类型
Recombinant
纯度
>90 % as determined by SDS-PAGE.
产品编号 ABIN7580930
Protein
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
人细胞
蛋白类型
Recombinant
产品编号 ABIN7890306
Protein
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 85 % as determined by reducing SDS-PAGE.
产品编号 ABIN7669630
Protein
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
人细胞
蛋白类型
Recombinant
产品编号 ABIN7890311
Protein
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
人细胞
蛋白类型
Recombinant
产品编号 ABIN7890310
Protein
  • ELISA (ELISA: 所列应用)
  • SDS (SDS-PAGE: 所列应用)
  • WB (Western Blotting: 所列应用)
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
Mammalian Cells
蛋白类型
Recombinant
纯度
>90 % as determined by SDS-PAGE.
产品编号 ABIN7580944
Protein
  • ELISA (ELISA: 所列应用)
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 95 % as determined by reducing SDS-PAGE.
生物活性
Active
产品编号 ABIN7669667
Protein
  • ELISA (ELISA: 所列应用)
  • SDS (SDS-PAGE: 所列应用)
  • WB (Western Blotting: 所列应用)
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
Insect Cells
蛋白类型
Recombinant
纯度
>90 % as determined by SDS-PAGE.
产品编号 ABIN7580950
Protein
  • ELISA (ELISA: 所列应用)
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 95 % as determined by reducing SDS-PAGE.
生物活性
Active
产品编号 ABIN7669649
Protein
  • ELISA (ELISA: 所列应用)
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 90 % as determined by reducing SDS-PAGE.
生物活性
Active
产品编号 ABIN7669657

Latest Publications for our SARS-CoV-2 Spike 蛋白

Gao, Yang, Dong, Tang, Cao, Ding, Zhu, Bai, Xia, Zhu, Zhao, Peng, Xu, Zhang: "A multi-antigen vaccinia vaccine broadly protected mice against SARS-CoV-2 and influenza A virus while also targeting SARS-CoV-1 and MERS-CoV." in: Frontiers in immunology, Vol. 15, pp. 1473428, (2024) (PubMed).

Yang, Liu, Jiang, Zhang, Fu, Li, Hu, Yuan: "Antibodies against SARS-CoV-2 non-structural protein 3 cross-react with human muscle cells and neuroglial cells." in: Vaccine, Vol. 42, Issue 6, pp. 1259-1267, (2024) (PubMed).

Mazunina, Gushchin, Bykonia, Kleymenov, Siniavin, Kozlova, Mukasheva, Shidlovskaya, Kuznetsova, Usachev, Zlobin, Burtseva, Ivanov, Logunov, Gintsburg: "Immunogenicity and Efficacy of Combined mRNA Vaccine Against Influenza and SARS-CoV-2 in Mice Animal Models." in: Vaccines, Vol. 12, Issue 11, (2024) (PubMed).

Wu, Cong, Wei, Hu, Sun, Ran, Liao, Zheng, Ye: "A Naïve Phage Display Library-Derived Nanobody Neutralizes SARS-CoV-2 and Three Variants of Concern." in: International journal of nanomedicine, Vol. 18, pp. 5781-5795, (2023) (PubMed).

Payam, Funari, Scamarcio, Bhalla: "Sensing Dynamically Evolved Short-Range Nanomechanical Forces in Fast-Mutating Single Viral Spike Proteins." in: Small science, Vol. 3, Issue 8, pp. 2300029, (2023) (PubMed).

Erickson, Logsdon, Rhea, Hansen, Holden, Banks, Smith, German, Farr, Morley, Weaver, Hirsch, Kovac, Kontsekova, Baumann, Omer, Raber: "Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 variants of concern induce neuroinflammation which is accentuated in a mouse model of Alzheimer's disease." in: Brain, behavior, and immunity, Vol. 109, pp. 251-268, (2023) (PubMed).

Meng, Zha, Zhou, Cao, Jiang, Zhu, Li, Lu, Zhang, Yang, Feng, Gu, Tang, Jiang, Li, Lavillette, Zhang: "A Spike-destructing human antibody effectively neutralizes Omicron-included SARS-CoV-2 variants with therapeutic efficacy." in: PLoS pathogens, Vol. 19, Issue 1, pp. e1011085, (2023) (PubMed).

Bohnacker, Hartung, Henkel, Quaranta, Kolmert, Priller, Ud-Dean, Giglberger, Kugler, Pechtold, Yazici, Lechner, Erber, Protzer, Lingor, Knolle, Chaker, Schmidt-Weber, Wheelock, Esser-von Bieren: "Mild COVID-19 imprints a long-term inflammatory eicosanoid- and chemokine memory in monocyte-derived macrophages." in: Mucosal immunology, Vol. 15, Issue 3, pp. 515-524, (2022) (PubMed).

Bhalla, Payam, Morelli, Sharma, Johnson, Thomson, Jolly, Canfarotta: "Nanoplasmonic biosensor for rapid detection of multiple viral variants in human serum." in: Sensors and actuators. B, Chemical, Vol. 365, pp. 131906, (2022) (PubMed).

Vogt, Augusto, Martina, Chang, Nasrallah, Speiser, Vogel, Bachmann, Mohsen: "Increased Receptor Affinity and Reduced Recognition by Specific Antibodies Contribute to Immune Escape of SARS-CoV-2 Variant Omicron." in: Vaccines, Vol. 10, Issue 5, (2022) (PubMed).

Aliases for SARS-CoV-2 Spike 蛋白

E2 glycoprotein precursor (S) 蛋白
Surface Glycoprotein (S) 蛋白
E2 蛋白
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