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SARS-CoV-2 Spike 蛋白

(SARS-CoV-2 Spike (SARS-CoV-2 S))
mediates fusion of the virion and cellular membranes by acting as a class I viral fusion protein. Under the current model, the protein has at least three conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.

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  • 抗原: SARS-CoV-2 Spike (SARS-CoV-2 S)
  • Protein
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN7454347
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, BA.2.75 - Omicron, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • 100 μg
  • 500 μg
发货至: 中国
ABIN7454349
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, BA.4.6 - Omicron, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • 100 μg
  • 500 μg
发货至: 中国
ABIN7454351
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD, XBB - Omicron, XBB.1.5 - Omicron) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • 100 μg
  • 500 μg
发货至: 中国
ABIN7454350
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • 100 μg
  • 500 μg
发货至: 中国
ABIN7454352
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD, XBB - Omicron) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • 100 μg
  • 500 μg
发货至: 中国
ABIN7665353
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, BA.4 - Omicron, Receptor Binding Domain) (His tag) SARS-CoV-2 S · Protein Coronavirus (CoV) HEK-293 Cells
  • ELISA (ELISA: 所列应用)
  • WB (Western Blotting: 所列应用)
  • 50 μg
  • 1 mg
  • 200 μg
发货至: 中国
ABIN7665352
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 16-1213) (His-Avi Tag) SARS-CoV-2 S · Protein Coronavirus (CoV) HEK-293 Cells
  • ELISA (ELISA: 所列应用)
  • WB (Western Blotting: 所列应用)
  • 50 μg
  • 1 mg
  • 200 μg
发货至: 中国
ABIN6961041
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, N501Y, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • 50 μg
  • 1 mg
  • 500 μg
发货至: 中国
ABIN6961042
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, N501Y, RBD) (Fc Tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • 50 μg
  • 1 mg
  • 500 μg
发货至: 中国
ABIN7884571
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (B.1.617.2 - delta, Trimer) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • WB (Western Blotting: 所列应用)
  • 100 μg
发货至: 中国
ABIN7884575
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (B.1.617.2 - delta, RBD) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • 100 μg
发货至: 中国
ABIN7385980
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) Insect Cells
  • WB (Western Blotting: 所列应用)
  • EIA (Enzyme Immunoassay: 所列应用)
  • 1 mg
发货至: 中国
ABIN7884570
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (Trimer) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • WB (Western Blotting: 所列应用)
  • 100 μg
发货至: 中国
ABIN7884567
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (Subunit S1) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) 大肠杆菌(E. Coli)
  • WB (Western Blotting: 所列应用)
  • 100 μg
发货至: 中国
ABIN7884568
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) 大肠杆菌(E. Coli)
  • WB (Western Blotting: 所列应用)
  • 100 μg
发货至: 中国
ABIN7884569
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) CHO Cells
  • WB (Western Blotting: 所列应用)
  • 5 μg
发货至: 中国
ABIN7884573
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (B.1.1.529 - Omicron, Trimer) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • 100 μg
发货至: 中国
ABIN7669698
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD) (mFc Tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • ELISA (ELISA: 所列应用)
  • BLI (Bio-Layer Interferometry: 所列应用)
  • 100 μg
发货至: 中国
ABIN7669683
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, G476S, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • ELISA (ELISA: 所列应用)
  • 100 μg
发货至: 中国
ABIN7669629
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • 100 μg
发货至: 中国
Protein
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
生物活性
Active
产品编号 ABIN7454347
100 μg (More quantities available)
发货至: 中国
获取报价
Protein
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
生物活性
Active
产品编号 ABIN7454349
100 μg (More quantities available)
发货至: 中国
获取报价
Protein
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
生物活性
Active
产品编号 ABIN7454351
100 μg (More quantities available)
发货至: 中国
获取报价
Protein
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
生物活性
Active
产品编号 ABIN7454350
100 μg (More quantities available)
发货至: 中国
获取报价
Protein
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
生物活性
Active
产品编号 ABIN7454352
100 μg (More quantities available)
发货至: 中国
获取报价
Protein
  • ELISA (ELISA: 所列应用)
  • WB (Western Blotting: 所列应用)
宿主
Coronavirus (CoV)
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
Greater than 90 % as determined by SDS-PAGE.
产品编号 ABIN7665353
50 μg (More quantities available)
发货至: 中国
获取报价
Protein
  • ELISA (ELISA: 所列应用)
  • WB (Western Blotting: 所列应用)
宿主
Coronavirus (CoV)
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
Greater than 90 % as determined by SDS-PAGE.
生物活性
Active
产品编号 ABIN7665352
50 μg (More quantities available)
发货至: 中国
获取报价
Protein
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
HEK-293 Cells
蛋白类型
Recombinant
产品编号 ABIN6961041
Protein
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
HEK-293 Cells
蛋白类型
Recombinant
产品编号 ABIN6961042
Protein
  • WB (Western Blotting: 所列应用)
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
>95 %
产品编号 ABIN7884571
Protein
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
HEK-293 Cells
蛋白类型
Recombinant
产品编号 ABIN7884575
Protein
  • WB (Western Blotting: 所列应用)
  • EIA (Enzyme Immunoassay: 所列应用)
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
Insect Cells
蛋白类型
Recombinant
产品编号 ABIN7385980
Protein
  • WB (Western Blotting: 所列应用)
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
>95 %
产品编号 ABIN7884570
Protein
  • WB (Western Blotting: 所列应用)
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
大肠杆菌(E. Coli)
蛋白类型
Recombinant
纯度
>98 %
产品编号 ABIN7884567
Protein
  • WB (Western Blotting: 所列应用)
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
大肠杆菌(E. Coli)
蛋白类型
Recombinant
纯度
>98 %
产品编号 ABIN7884568
Protein
  • WB (Western Blotting: 所列应用)
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
CHO Cells
蛋白类型
Recombinant
纯度
>98 %
产品编号 ABIN7884569
Protein
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
>90 %
产品编号 ABIN7884573
Protein
  • ELISA (ELISA: 所列应用)
  • BLI (Bio-Layer Interferometry: 所列应用)
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 95 % as determined by reducing SDS-PAGE.
生物活性
Active
产品编号 ABIN7669698
Protein
  • ELISA (ELISA: 所列应用)
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 95 % as determined by reducing SDS-PAGE.
生物活性
Active
产品编号 ABIN7669683
Protein
宿主
SARS Coronavirus-2 (SARS-CoV-2)
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 85 % as determined by reducing SDS-PAGE.
产品编号 ABIN7669629

Latest Publications for our SARS-CoV-2 Spike 蛋白

Gao, Yang, Dong, Tang, Cao, Ding, Zhu, Bai, Xia, Zhu, Zhao, Peng, Xu, Zhang: "A multi-antigen vaccinia vaccine broadly protected mice against SARS-CoV-2 and influenza A virus while also targeting SARS-CoV-1 and MERS-CoV." in: Frontiers in immunology, Vol. 15, pp. 1473428, (2024) (PubMed).

Yang, Liu, Jiang, Zhang, Fu, Li, Hu, Yuan: "Antibodies against SARS-CoV-2 non-structural protein 3 cross-react with human muscle cells and neuroglial cells." in: Vaccine, Vol. 42, Issue 6, pp. 1259-1267, (2024) (PubMed).

Mazunina, Gushchin, Bykonia, Kleymenov, Siniavin, Kozlova, Mukasheva, Shidlovskaya, Kuznetsova, Usachev, Zlobin, Burtseva, Ivanov, Logunov, Gintsburg: "Immunogenicity and Efficacy of Combined mRNA Vaccine Against Influenza and SARS-CoV-2 in Mice Animal Models." in: Vaccines, Vol. 12, Issue 11, (2024) (PubMed).

Wu, Cong, Wei, Hu, Sun, Ran, Liao, Zheng, Ye: "A Naïve Phage Display Library-Derived Nanobody Neutralizes SARS-CoV-2 and Three Variants of Concern." in: International journal of nanomedicine, Vol. 18, pp. 5781-5795, (2023) (PubMed).

Payam, Funari, Scamarcio, Bhalla: "Sensing Dynamically Evolved Short-Range Nanomechanical Forces in Fast-Mutating Single Viral Spike Proteins." in: Small science, Vol. 3, Issue 8, pp. 2300029, (2023) (PubMed).

Erickson, Logsdon, Rhea, Hansen, Holden, Banks, Smith, German, Farr, Morley, Weaver, Hirsch, Kovac, Kontsekova, Baumann, Omer, Raber: "Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 variants of concern induce neuroinflammation which is accentuated in a mouse model of Alzheimer's disease." in: Brain, behavior, and immunity, Vol. 109, pp. 251-268, (2023) (PubMed).

Meng, Zha, Zhou, Cao, Jiang, Zhu, Li, Lu, Zhang, Yang, Feng, Gu, Tang, Jiang, Li, Lavillette, Zhang: "A Spike-destructing human antibody effectively neutralizes Omicron-included SARS-CoV-2 variants with therapeutic efficacy." in: PLoS pathogens, Vol. 19, Issue 1, pp. e1011085, (2023) (PubMed).

Bohnacker, Hartung, Henkel, Quaranta, Kolmert, Priller, Ud-Dean, Giglberger, Kugler, Pechtold, Yazici, Lechner, Erber, Protzer, Lingor, Knolle, Chaker, Schmidt-Weber, Wheelock, Esser-von Bieren: "Mild COVID-19 imprints a long-term inflammatory eicosanoid- and chemokine memory in monocyte-derived macrophages." in: Mucosal immunology, Vol. 15, Issue 3, pp. 515-524, (2022) (PubMed).

Bhalla, Payam, Morelli, Sharma, Johnson, Thomson, Jolly, Canfarotta: "Nanoplasmonic biosensor for rapid detection of multiple viral variants in human serum." in: Sensors and actuators. B, Chemical, Vol. 365, pp. 131906, (2022) (PubMed).

Vogt, Augusto, Martina, Chang, Nasrallah, Speiser, Vogel, Bachmann, Mohsen: "Increased Receptor Affinity and Reduced Recognition by Specific Antibodies Contribute to Immune Escape of SARS-CoV-2 Variant Omicron." in: Vaccines, Vol. 10, Issue 5, (2022) (PubMed).

Aliases for SARS-CoV-2 Spike 蛋白

E2 glycoprotein precursor (S) 蛋白
Surface Glycoprotein (S) 蛋白
E2 蛋白
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