SARS-CoV-2 Spike 蛋白
(SARS-CoV-2 Spike (SARS-CoV-2 S))
mediates fusion of the virion and cellular membranes by acting as a class I viral fusion protein. Under the current model, the protein has at least three conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
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| SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, BA.5 - Omicron, RBD) (Fc Tag) | SARS Coronavirus-2 (SARS-CoV-2) | HEK-293 Cells |
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| SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, B.1.1.529 - Omicron, RBD) (Fc Tag) | SARS Coronavirus-2 (SARS-CoV-2) | HEK-293 Cells |
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| SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 16-1188, Trimer) (Fc Tag) | SARS Coronavirus-2 (SARS-CoV-2) | HEK-293 Cells |
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| SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (B.1.617.2 - delta, RBD) (His-SUMO Tag) | SARS Coronavirus-2 (SARS-CoV-2) | HEK-293 Cells |
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| SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (RBD) (His-SUMO Tag) | SARS Coronavirus-2 (SARS-CoV-2) | HEK-293 Cells |
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| SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (B.1.351 - beta, Trimer) (His tag) | SARS Coronavirus-2 (SARS-CoV-2) | HEK-293 Cells |
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| SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (B.1.351 - beta, RBD) (Fc Tag) | SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Beta | HEK-293 Cells |
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| SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (B.1.1.7 - alpha, Trimer) (His tag,AVI tag,Biotin) | SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Alpha | HEK-293 Cells |
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| SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (P.1 - gamma, Trimer) (His tag,AVI tag,Biotin) | SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Gamma | HEK-293 Cells |
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| SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (B.1.351 - beta, Trimer) (His tag) | SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Beta | HEK-293 Cells |
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| SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (P.1 - gamma) (His tag) | SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Gamma | HEK-293 Cells |
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| SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (E484K, K417T, N501Y, RBD) (His tag,AVI tag,Biotin) | SARS Coronavirus-2 (SARS-CoV-2) | HEK-293 Cells |
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| SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (B.1.1.529 - Omicron, Trimer) (His-Avi Tag,Biotin) | SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron | HEK-293 Cells |
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| SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (B.1.1.529 - Omicron, Trimer) (His tag) | SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron | HEK-293 Cells |
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| SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (B.1.1.529 - Omicron, RBD) (His-Avi Tag,Biotin) | SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron | HEK-293 Cells |
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| SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (RBD) (mFc Tag,AVI tag,Biotin) | SARS Coronavirus-2 (SARS-CoV-2) | HEK-293 Cells |
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| SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (RBD) (mFc Tag,AVI tag,Biotin) | SARS Coronavirus-2 (SARS-CoV-2) | HEK-293 Cells |
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| SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (E484K, K417N, N501Y, RBD) (His tag,AVI tag,Biotin) | SARS Coronavirus-2 (SARS-CoV-2) | HEK-293 Cells |
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| SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (B.1.1.529 - Omicron, NTD) (His tag) | SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron | HEK-293 Cells |
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| SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (B.1.351 – beta) | SARS Coronavirus-2 (SARS-CoV-2) | Mammalian Cells |
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Protein
- SDS (SDS-PAGE: 有验证图片)
- IA (Immunoassay: 所列应用)
- AM (Affinity Measurement: 所列应用)
- ADA (Antibody Drug Assay: 所列应用)
- ScA (Screening Assay: 所列应用)
- 宿主
- SARS Coronavirus-2 (SARS-CoV-2)
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- SDS (SDS-PAGE: 有验证图片)
- IA (Immunoassay: 所列应用)
- AM (Affinity Measurement: 所列应用)
- ADA (Antibody Drug Assay: 所列应用)
- ScA (Screening Assay: 所列应用)
- 宿主
- SARS Coronavirus-2 (SARS-CoV-2)
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- ELISA (ELISA: 有验证图片)
- 宿主
- SARS Coronavirus-2 (SARS-CoV-2)
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- SARS Coronavirus-2 (SARS-CoV-2)
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >98 %
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- SARS Coronavirus-2 (SARS-CoV-2)
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >98 %
Protein
- WB (Western Blotting: 有验证图片)
- 宿主
- SARS Coronavirus-2 (SARS-CoV-2)
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 %
Protein
- ELISA (ELISA: 有验证图片)
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Beta
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- ELISA (ELISA: 有验证图片)
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Alpha
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- ELISA (ELISA: 有验证图片)
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Gamma
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- ELISA (ELISA: 有验证图片)
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Beta
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >90 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- ELISA (ELISA: 有验证图片)
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Gamma
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- ELISA (ELISA: 有验证图片)
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- SARS Coronavirus-2 (SARS-CoV-2)
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >90 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- ELISA (ELISA: 有验证图片)
- SDS (SDS-PAGE: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- 宿主
- SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95% as determined by SDS-PAGE. > 95% as determined by SEC-MALS.
Protein
- ELISA (ELISA: 有验证图片)
- SDS (SDS-PAGE: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- 宿主
- SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95% as determined by SDS-PAGE. > 95% as determined by SEC-MALS.
Protein
- ELISA (ELISA: 有验证图片)
- SDS (SDS-PAGE: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- 宿主
- SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95% as determined by SDS-PAGE.
Protein
- ELISA (ELISA: 有验证图片)
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- SARS Coronavirus-2 (SARS-CoV-2)
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- ELISA (ELISA: 有验证图片)
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- SARS Coronavirus-2 (SARS-CoV-2)
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- ELISA (ELISA: 有验证图片)
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- SARS Coronavirus-2 (SARS-CoV-2)
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- ELISA (ELISA: 有验证图片)
- SDS (SDS-PAGE: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- 宿主
- SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95% as determined by SDS-PAGE. > 95% as determined by SEC-MALS.
Protein
- 宿主
- SARS Coronavirus-2 (SARS-CoV-2)
- 宿主
- Mammalian Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Latest Publications for our SARS-CoV-2 Spike 蛋白
: "A multi-antigen vaccinia vaccine broadly protected mice against SARS-CoV-2 and influenza A virus while also targeting SARS-CoV-1 and MERS-CoV." in: Frontiers in immunology, Vol. 15, pp. 1473428, (2024) (PubMed).
: "Antibodies against SARS-CoV-2 non-structural protein 3 cross-react with human muscle cells and neuroglial cells." in: Vaccine, Vol. 42, Issue 6, pp. 1259-1267, (2024) (PubMed).
: "Immunogenicity and Efficacy of Combined mRNA Vaccine Against Influenza and SARS-CoV-2 in Mice Animal Models." in: Vaccines, Vol. 12, Issue 11, (2024) (PubMed).
: "A Naïve Phage Display Library-Derived Nanobody Neutralizes SARS-CoV-2 and Three Variants of Concern." in: International journal of nanomedicine, Vol. 18, pp. 5781-5795, (2023) (PubMed).
: "Sensing Dynamically Evolved Short-Range Nanomechanical Forces in Fast-Mutating Single Viral Spike Proteins." in: Small science, Vol. 3, Issue 8, pp. 2300029, (2023) (PubMed).
: "Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 variants of concern induce neuroinflammation which is accentuated in a mouse model of Alzheimer's disease." in: Brain, behavior, and immunity, Vol. 109, pp. 251-268, (2023) (PubMed).
: "A Spike-destructing human antibody effectively neutralizes Omicron-included SARS-CoV-2 variants with therapeutic efficacy." in: PLoS pathogens, Vol. 19, Issue 1, pp. e1011085, (2023) (PubMed).
: "Mild COVID-19 imprints a long-term inflammatory eicosanoid- and chemokine memory in monocyte-derived macrophages." in: Mucosal immunology, Vol. 15, Issue 3, pp. 515-524, (2022) (PubMed).
: "Nanoplasmonic biosensor for rapid detection of multiple viral variants in human serum." in: Sensors and actuators. B, Chemical, Vol. 365, pp. 131906, (2022) (PubMed).
: "Increased Receptor Affinity and Reduced Recognition by Specific Antibodies Contribute to Immune Escape of SARS-CoV-2 Variant Omicron." in: Vaccines, Vol. 10, Issue 5, (2022) (PubMed).
: "Antibodies against SARS-CoV-2 non-structural protein 3 cross-react with human muscle cells and neuroglial cells." in: Vaccine, Vol. 42, Issue 6, pp. 1259-1267, (2024) (PubMed).
: "Immunogenicity and Efficacy of Combined mRNA Vaccine Against Influenza and SARS-CoV-2 in Mice Animal Models." in: Vaccines, Vol. 12, Issue 11, (2024) (PubMed).
: "A Naïve Phage Display Library-Derived Nanobody Neutralizes SARS-CoV-2 and Three Variants of Concern." in: International journal of nanomedicine, Vol. 18, pp. 5781-5795, (2023) (PubMed).
: "Sensing Dynamically Evolved Short-Range Nanomechanical Forces in Fast-Mutating Single Viral Spike Proteins." in: Small science, Vol. 3, Issue 8, pp. 2300029, (2023) (PubMed).
: "Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 variants of concern induce neuroinflammation which is accentuated in a mouse model of Alzheimer's disease." in: Brain, behavior, and immunity, Vol. 109, pp. 251-268, (2023) (PubMed).
: "A Spike-destructing human antibody effectively neutralizes Omicron-included SARS-CoV-2 variants with therapeutic efficacy." in: PLoS pathogens, Vol. 19, Issue 1, pp. e1011085, (2023) (PubMed).
: "Mild COVID-19 imprints a long-term inflammatory eicosanoid- and chemokine memory in monocyte-derived macrophages." in: Mucosal immunology, Vol. 15, Issue 3, pp. 515-524, (2022) (PubMed).
: "Nanoplasmonic biosensor for rapid detection of multiple viral variants in human serum." in: Sensors and actuators. B, Chemical, Vol. 365, pp. 131906, (2022) (PubMed).
: "Increased Receptor Affinity and Reduced Recognition by Specific Antibodies Contribute to Immune Escape of SARS-CoV-2 Variant Omicron." in: Vaccines, Vol. 10, Issue 5, (2022) (PubMed).
Aliases for SARS-CoV-2 Spike 蛋白
E2 glycoprotein precursor (S) 蛋白Surface Glycoprotein (S) 蛋白
E2 蛋白
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