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Human VEGFC ELISA Kit for Sandwich ELISA - ABIN411382
Zhao, Sun, Li: Expression and clinical significance of STAT3, P-STAT3, and VEGF-C in small cell lung cancer. in Asian Pacific journal of cancer prevention : APJCP 2012
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Human VEGFC ELISA Kit for Sandwich ELISA - ABIN625369
Yue, Xu, Zhu, Zhang, Liu: Over-expression of nerve growth factor-β in human cholangiocarcinoma QBC939 cells promote tumor progression. in PLoS ONE 2013
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Human VEGFC ELISA Kit for Sandwich ELISA - ABIN414935
You, Bei, Cheng, Cheng: Expression of COX-2 and VEGF-C in cholangiocarcinomas at different clinical and pathological stages. in Genetics and molecular research : GMR 2015
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Mouse (Murine) VEGFC ELISA Kit for Sandwich ELISA - ABIN415601
Zhang, Wang, Gao, Guo, Chen, Wang, Gao, Rao, Chen: Alternatively activated RAW264.7 macrophages enhance tumor lymphangiogenesis in mouse lung adenocarcinoma. in Journal of cellular biochemistry 2009
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Mouse (Murine) VEGFC ELISA Kit for Sandwich ELISA - ABIN365459
Shimizu, Shibata, Shintani, Ishii, Murohara: Therapeutic lymphangiogenesis with implantation of adipose-derived regenerative cells. in Journal of the American Heart Association 2012
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Human VEGFC ELISA Kit for Sandwich ELISA - ABIN365328
Tang, Jiang, Guo, Si, Jiao: Expression and significance of vascular endothelial growth factor A and C in leukemia central nervous system metastasis. in Leukemia research 2013
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Vegfc acts through ERK (显示 MAPK1 ELISA试剂盒) to induce sprouting and differentiation of trunk lymphatic progenitors.
data not only reveal a non-canonical function of Mt2 (显示 MT2 ELISA试剂盒) in angiogenesis, but also propose Mt2 (显示 MT2 ELISA试剂盒) as a novel regulator of vegfc expression.
Vegfc signaling increases mafba (显示 MAFB ELISA试剂盒) expression to control downstream transcription
Vegfc is dispensable for facial lymphatic sprouting but not for the complete development of the facial lymphatic network.
In the embryo, phenotypes driven by increased Vegfc are suppressed in the absence of Ccbe1 (显示 CCBE1 ELISA试剂盒), and Vegfc-driven sprouting is enhanced by local Ccbe1 (显示 CCBE1 ELISA试剂盒) overexpression. Moreover, Vegfc- and Vegfr3 (显示 FLT4 ELISA试剂盒)-dependent Erk (显示 MAPK1 ELISA试剂盒) signaling is impaired in the absence of Ccbe1 (显示 CCBE1 ELISA试剂盒).
Vegfc has an essential role in lymphangiogenesis [review]
The parallel growth of motoneuron axons with the dorsal aorta depends on Vegfc/Vegfr3 (显示 FLT4 ELISA试剂盒) signaling in zebrafish.
Vegfc acts in two distinct modes during development: as a paracrine factor secreted from arteries to guide closely associated lymphatic vasculature and as an autocrine factor to drive migratory persistence during angiogenesis.
Rspo1-Wnt-VegfC-Vegfr3 signaling plays a crucial role as an endothelial-autonomous permissive cue for developmental angiogenesis.
Here, we show that vascular endothelial growth factor C (Vegfc), an angiogenic as well as a lymphangiogenic factor, is unexpectedly involved in this process in zebrafish.
VEGF-C and VEGF-C156S genes have roles in the pro-lymphangiogenic growth factor therapy of lymphedema
Transcription of the vascular endothelial growth factor C gene (VEGF-C) and translation of the corresponding protein were significantly up-regulated in swine umbilical vein endothelial cells with classical swine fever virus acute infection.
No difference in bioactivity was detected between porcine relaxin-1 (显示 RLN1 ELISA试剂盒) and recombinant human relaxin-2 (显示 RLN1 ELISA试剂盒) in either mice or rats.
During progressive ischemia, functional and metabolic benefits of intramyocardial VEGF-C gene transfer were apparent. VEGF-C-induced collateral formation occurred at the site of gene transfer
document for the first time that CCL5 (显示 CCL5 ELISA试剂盒) induces tumor lymphangiogenesis by the induction of VEGF-C in human cancer cells.
Data suggest that the BRG1 (显示 SMARCA4 ELISA试剂盒)/STAT3 (显示 STAT3 ELISA试剂盒)/VEGFC in tumor-associated lymphangiogenesis might lead to the discovery of novel therapeutic targets in the treatment of cancers with BRG1 (显示 SMARCA4 ELISA试剂盒) loss of function.
Studied the effect of recombinant human vascular endothelial growth factor (VEGF)-C on lymphangiogenesis, inflammation, and fibrosis in the mouse kidney using the unilateral ureteral obstruction (UUO); lymphangiogenesis was significantly induced in the UUO+VEGF-C group. In lymphatic endothelial cells, VEGF-C increased the activity and proliferation of such cells and expression of VCAM-1.
In multivariate analysis, only serum VEGF-A (显示 VEGFA ELISA试剂盒) correlated to diabetes duration, whereas VEGF-C only correlated to HbA1c and fasting blood glucose.
This study reports that human dendritic cells produce VEGF-C, a cytokine with potent pro-lymphangiogenic activity when stimulated with IFN-gamma (显示 IFNG ELISA试剂盒)
Association of coexpressed high levels of VEGF-C and active MMP-9 (显示 MMP9 ELISA试剂盒) with lymphatic spreading and local invasiveness of Papillary thyroid carcinoma (PTC (显示 F9 ELISA试剂盒)) suggests their potential usefulness as predictive biomarkers of aggressive PTC (显示 F9 ELISA试剂盒) behavior.
Data show that VEGF-C, VEGF-D (显示 Figf ELISA试剂盒), and VEGFR-3 (显示 FLT4 ELISA试剂盒) were expressed in a substantial percentage of breast carcinomas.
By treating LECs with VEGF (显示 VEGFA ELISA试剂盒)-C156S and analyzing subsequent changes in gene expression, we identified several 'immediate early (显示 JUN ELISA试剂盒)' transcription factors that showed a rapid transient upregulation VEGFR-3 (显示 FLT4 ELISA试剂盒) stimulation. these results reveal an important and unanticipated role of HOXD10 (显示 HOXD10 ELISA试剂盒) in the regulation of VEGFR-3 (显示 FLT4 ELISA试剂盒) signaling in lymphatic endothelial cells, and in the control of lymphangiogenesis and permeability.
In colon cancer samples, there was a positive correlation between the expression of integrin alpha4 and VEGF-C. Integrin alpha4 and VEGF-C were significantly associated with the clinicopathological parameters (LMVD, Duke's stage, and lymph node metastasis). patients with high integrin alpha4 or VEGF-C expression had significantly shorter overall survival and tumor-free survival time.
High VEGFC expression is associated with angiogenesis and lymphangiogenesis.
lymphangiogenesis is regulated by two distinct proteolytic mechanisms of ligand activation: one in which VEGFC activation by ADAMTS3 (显示 Adamts2 ELISA试剂盒) and CCBE1 (显示 CCBE1 ELISA试剂盒) spatially and temporally patterns developing lymphatics, and one in which VEGFD (显示 Figf ELISA试剂盒) activation by a distinct proteolytic mechanism may be stimulated during inflammatory lymphatic growth
These results reveal an unexpected role for VEGF-C, a major lymphangiogenic growth factor, in the transition to fetal liver erythropoiesis.
Results suggest that interleukin-6 (IL-6 (显示 IL6 ELISA试剂盒)) increases VEGF-C induction and lymphangiogenesis may involve, at least in part, Src (显示 SRC ELISA试剂盒)-FAK (显示 PTK2 ELISA试剂盒)-STAT3 (显示 STAT3 ELISA试剂盒) cascade in lymphatic endothelial cells (LECs).
Data show that heparanase-1 (HPA-1 (显示 HPSE ELISA试剂盒)) induced shedding of heparan sulfate chain from syndecan-1 (SDC-1 (显示 SDC1 ELISA试剂盒)) facilitated the release of vascular endothelial growth factor C (VEGF-C) from SDC-1 (显示 SDC1 ELISA试剂盒)/VEGF-C complex into the medium of hepatocarcinoma cell.
Data show that in the MCF-7 breast cancer cell line, only MT1X metallothioneins (MTs (显示 NEU2 ELISA试剂盒)) positively correlated with vascular endothelial growth factor C (VEGFC).
The findings in this study strongly suggest the following: i) that VEGF-C promotes the proliferative activity and migratory ability of mesenchymal stem cell ; and ii) VEGF-C and Tgfb (显示 TGFB1 ELISA试剂盒) reciprocally regulate mesenchymal stem cell commitment to differentiation into lymphatic endothelial or osteoblastic phenotypes, respectively.
The authors show that VEGF-C is necessary for perinatal lymphangiogenesis, but required for adult lymphatic vessel maintenance only in the intestine.
MT1-MMP (显示 MMP14 ELISA试剂盒) directly cleaves LYVE-1 (显示 LYVE1 ELISA试剂盒) on lymphatic endothelial cells to inhibit LYVE-1 (显示 LYVE1 ELISA试剂盒)-mediated lymphangiogenic responses and restrains the production of VEGF-C.
HA increases lymphangiogenesis in renal fibrosis model and also stimulates vascular endothelial cell growth factor (显示 FGF1 ELISA试剂盒)-C production from macrophages through Toll-like receptor 4 (显示 TLR4 ELISA试剂盒)-dependent signal pathway
Results showed that the VEGF-C/VEGFR-3 (显示 FLT4 ELISA试剂盒) system underlies the protective effect of ischemic preconditioning against forebrain ischemia in the mouse hippocampus
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.
vascular endothelial growth factor C
, vascular endothelial growth factor c
, FLT4 ligand DHM
, vascular endothelial growth factor-related protein
, flt4 ligand
, vascular endothelial growth factor C isoform 129
, vascular endothelial growth factor C isoform 184