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抗Human BDNF 抗体:
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抗Mouse (Murine) BDNF 抗体:
Dog (Canine) Polyclonal BDNF Primary Antibody for IHC, WB - ABIN2777093
Hashimoto, Moriguchi, Yamashita, Mori, Nemoto, Okada, Hori, Noguchi, Kunugi, Ohnishi: Dose-dependent effect of the Val66Met polymorphism of the brain-derived neurotrophic factor gene on memory-related hippocampal activity. in Neuroscience research 2008
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Human Polyclonal BDNF Primary Antibody for CyTOF, FACS - ABIN4899237
Xapelli, Bernardino, Ferreira, Grade, Silva, Salgado, Cavadas, Grouzmann, Poulsen, Jakobsen, Oliveira, Zimmer, Malva: Interaction between neuropeptide Y (NPY) and brain-derived neurotrophic factor in NPY-mediated neuroprotection against excitotoxicity: a role for microglia. in The European journal of neuroscience 2008
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Human Polyclonal BDNF Primary Antibody for IF (p), IHC (p) - ABIN1387788
Zhao, Li, Wei, Savage, Zhou, Ma: Ketamine administered to pregnant rats in the second trimester causes long-lasting behavioral disorders in offspring. in Neurobiology of disease 2014
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Human Polyclonal BDNF Primary Antibody for EIA, Func - ABIN115986
Hartog, Dittrich, Pieneman, Jansen, Frankl-Vilches, Lessmann, Lilliehook, Goldman, Gahr: Brain-derived neurotrophic factor signaling in the HVC is required for testosterone-induced song of female canaries. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2009
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Human Polyclonal BDNF Primary Antibody for EIA, Func - ABIN115985
Miknyoczki, Wan, Chang, Dobrzanski, Ruggeri, Dionne, Buchkovich: The neurotrophin-trk receptor axes are critical for the growth and progression of human prostatic carcinoma and pancreatic ductal adenocarcinoma xenografts in nude mice. in Clinical cancer research : an official journal of the American Association for Cancer Research 2002
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Dog (Canine) Polyclonal BDNF Primary Antibody for WB - ABIN2777092
Galindo, Soslow, Brinkmeyer-Langford, Gupte, Smith, Sengsayadeth, Sawyer, Benson, Kornegay, Markham: Translating golden retriever muscular dystrophy microarray findings to novel biomarkers for cardiac/skeletal muscle function in Duchenne muscular dystrophy. in Pediatric research 2016
Human Monoclonal BDNF Primary Antibody for ICC, ELISA - ABIN1724944
Yoshida, Ishikawa, Niitsu, Nakazato, Watanabe, Shiraishi, Shiina, Hashimoto, Kanahara, Hasegawa, Enohara, Kimura, Iyo, Hashimoto: Decreased serum levels of mature brain-derived neurotrophic factor (BDNF), but not its precursor proBDNF, in patients with major depressive disorder. in PLoS ONE 2012
Human Polyclonal BDNF Primary Antibody for ELISA, ICC - ABIN6260247
Ge, Xie, Zhang, Tan, Wan, Wang, Jin: Differential Expression of miRNAs in the Hippocampi of Offspring Rats Exposed to Fluorine Combined with Aluminum during the Embryonic Stage and into Adulthood. in Biological trace element research 2018
polymorphisms in BDNF gene including rs925946, rs10501087, rs6265 and rs988712 can be considered as genetic determinants of obesity (systematic review and meta-analysis).
Single nucleotide polymorphism found in the BDNF-AS (BDNF antisense RNA [nonprotein coding]) gene may be related to the decreased plasma brain derived neurotrophic factor levels found in frail elderly people.
The pattern of low BDNF and high inflammation in MDD may be influenced by the Val66Met polymorphism; the association of a polymorphism in the BDNF gene with inflammatory markers in addition to BDNF levels suggests an interaction between these systems.
Angiogenin (显示 ANG 抗体) contributes to angiogenesis induced by Brain-derived neurotrophic factor (BDNF).
Study suggested that BDNF 196 G>A polymorphism may be a genetic marker for predicting insulin (显示 INS 抗体) resistance before initiating risperidone treatment in autism spectrum disorder patients.
No significant difference was found in the BDNF Val66Met polymorphism between patients with GAD (显示 GAD1 抗体) and healthy controls, nor was this polymorphism significantly associated with antidepressant drug efficacy for GAD (显示 GAD1 抗体)
BDNF rs11030101 and BDNF rs61888800are associated with change of temperament scores in a clinical sample of subjects with major depression (MDD), who received selective serotonin reuptake inhibitor treatment.
We found that harsh parenting predicted an increased error-related negativity only among children with a methionine allele of the BDNF genotype, and evidence of moderated mediation: the ERN mediated the relationship between parenting and internalizing diagnoses and dimensional symptoms only if children had a methionine allele.
Findings presented here suggest a strong influence of seasonality on depression outcome and BDNF expression in atopic dermatitis and psoriasis
Serum BDNF was significantly lower in patients with Parkinson's disease than in patients with essential tremor and controls.
These observations suggest that GGA administration is a therapeutic candidate for depressive diseases by increasing hippocampal BDNF levels via HSP105 (显示 HSPH1 抗体) expression.
In a model of traumatic brain injury, transcranial ultrasound stimulation increases brain BDNF levels.
Results suggest that brain derived neurotrophic factor (BDNF) activation in the nucleus accumbens (NAc (显示 NLRP1 抗体)) may overcome memory and plasticity deficits linked to Actl6a (显示 BAF53A 抗体) protein (BAF53b (显示 ACTL6B 抗体)) mutations.
Upregulating BDNF-AS inhibits osteogenesis, possibly through inverse regulation on BDNF and osteogenic signaling pathways
miR (显示 MLXIP 抗体)-322 promotes Tau phosphorylation via negatively controlling BDNF-TrkB (显示 NTRK2 抗体) receptor activation
BDNF preserves intestinal mucosal barrier function and alters gut (显示 GUSB 抗体) microbiota in mice.
Results demonstrate that heterotrimeric Galphai1 and Galphai3 (显示 GNAI3 抗体) proteins are essential for TrkB (显示 NTRK2 抗体) signaling and that disruption of Galphai1 or Galphai3 (显示 GNAI3 抗体) function could contribute to depressive behaviors.
Stress from escapable electroshock (ES) was associated with up-regulation of brain-derived neurotrophic factor in amygdala as well as medial prefrontal cortex (mPFC). Stres from inescapable shock suppressed c-fos in mPFC (0 h) but induced more Arc (显示 NOL3 抗体) in amygdala (2 h) in comparison with ES.
The present study revealed that long-term exercise increased BDNF expression in the motor cortex and facilitated a transfer of motor learning from aerobic exercise to postural coordination.
These results suggested that the effects of Valeriana fauriei (VF) extract on a model of fibromyalgia (FM)may be associated with its modulatory effects on the BDNF signaling pathway in the hippocampus and medial prefrontal cortex. In conclusion, the mechanism underlying the protective effects of VF as a therapeutic agent against FM may involve the BDNF signaling pathway
BDNF is involved in the gonadal function of adult zebrafish, and mainly in the adult ovary.
One of the modulators of TOR (显示 FRAP1 抗体) is brain-derived neurotrophic factor (BDNF), which activates the TOR (显示 FRAP1 抗体) signaling pathway to promote protein synthesis, synapse strengthening, and the creation of new neural networks.findings demonstrate that TOR (显示 FRAP1 抗体) activation in old animals occurs in the early phase of consolidation, and follows a pattern identical to that of BDNF expression.
These results suggest an involvement of the BDNF/TrkB (显示 NTRK2 抗体) system in the regulation of food intake and energy balance in zebrafish, as in mammals
BDNF-TrkB (显示 NTRK2 抗体) influences the expression level of components of chemokine (显示 CCL1 抗体) signaling including Cxcr4b, and the generation of progenitors of mechanoreceptors, at the level of expression of Atoh1a-Atp2b1a.
Light regulates the expression of the BDNF/TrkB2 (显示 NTRK2 抗体) system in the adult zebrafish retina.
Brain-derived neurotrophic factor (BDNF) induces polarized signaling of small GTPase (显示 RACGAP1 抗体) (Rac1 (显示 RAC1 抗体)) protein at the onset of Schwann cell myelination through partitioning-defective 3 (Par3 (显示 PARD3 抗体)) protein.
the results demonstrate that bdnf mediates non-cell-autonomous maintenance of position and thereby the identity of differentiated neurons
The present results demonstrate that there is a parallel time-related decline in the expression of BDNF and TrkB (显示 NTRK2 抗体) in zebrafish.
The cloning and analysis of three additional zebrafish (Danio rerio) BDNF gene exons and two associated promoters, is reported. Among them are two exons that generate a novel tripartite mature transcript
Loss of BDNF is a major cause of the developmental abnormalities seen with huntingtin (显示 HTT 抗体) knockdown in zebrafish.
Together these results suggest an important role of BDNF in the maintenance and regeneration of the olfactory system.
BDNF suppresses neuromuscular junction maturation through cAMP-PKA signaling pathway
Findings demonstrate the neurotrophin, BDNF-dependent formation of integrin beta1-based adhesions in the growth cone and reveal how a positive regulator of substrate adhesions can block the negative remodeling and growth inhibitory effects of myelin-associated glycoprotein (显示 MAG 抗体) .
These results indicate that brief sensory stimulation, by initiating nuclear transcription and de novo protein synthesis of BDNF, can facilitate the refinement of response properties in the developing visual system.
In the Xenopus melanotrope, BDNF biosynthesis and processing occur along the secretory granule maturation axis, together with that of POMC (显示 POMC 抗体)-derived alphaMSH (显示 POMC 抗体), and that the light controls the biosynthesis and secretion of BDNF and of POMC (显示 POMC 抗体) end-products.
BDNF released from the neural lobe of the pituitary gland acts as a neurohormone stimulating the secretory activity of the melanotrope cells in the intermediate pituitary lobe.
BDNF influences synaptic connectivity in multiple ways, promoting not only the morphological maturation of axonal arbors but also their stabilization, but also their stabilization.
BDNF, in addition to its neural and hormonal roles, can be released as a neurohormone from the neural pituitary lobe of X. laevis
BDNF induces glial cell proliferation as well as axonal outgrowth and myelination in vivo.
PACAP stimulates the expression of BDNF transcript IV.
Lf upregulated several canonical signaling pathways associated with neurodevelopment and cognition and influenced ~10 genes involved in the brain-derived neurotrophin factor (BDNF) signaling pathway.
Taken together, these data indicate that recurrent tethering stress in sows over 4.5 years results in a loss of neurotrophic support by BDNF, mediated by an overactive neuroendocrine system.
FiO2 used for resuscitation affects matrix metalloproteinases MMP-9 (显示 MMP9 抗体) and MMP-2 (显示 MMP2 抗体), caspase-3 (显示 CASP3 抗体) and BDNF
These observations provided evidence that brain-derived naeurotrophic factor(BDNF) and its receptor (BDNF receptor) secreted by bovine sperm was important in regulation of insulin (显示 INS 抗体) and leptin (显示 LEP 抗体).
Expressed in ganglionic neuron-like tumor cells, which may activate an embryonic pathway involving BDNF.
Study showed that complex relationships exist between BDNF/TrkB (显示 NTRK2 抗体) gene expression and interneuron marker gene expression that appear to be dependent on the presence of testosterone at adolescence
In a monkey model, cortical BDNF and activity regulated cytoskeletal-associated protein ARC (显示 Arc 抗体) expressions are strongly correlated with spontaneous physical activity.
A SNP is present in rhesus macaques and is able to affect BDNF peripheral levels, thus making this primate model a fundamental tool to study gene by environment interactions involving the BDNF gene.
In monkey the decline of the BDNF protein level started earlier in the sensory and motor neocortical areas than in the association neocortical areas.
The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene.
, brain derived neurothrophic factor
, brain derived neurotrophic factor
, anorexia BDNF
, brain-derived neurotrophic factor
, neurotrophic factor