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抗Human BDNF 抗体:
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抗Mouse (Murine) BDNF 抗体:
Dog (Canine) Polyclonal BDNF Primary Antibody for IHC, WB - ABIN2777093
Hashimoto, Moriguchi, Yamashita, Mori, Nemoto, Okada, Hori, Noguchi, Kunugi, Ohnishi: Dose-dependent effect of the Val66Met polymorphism of the brain-derived neurotrophic factor gene on memory-related hippocampal activity. in Neuroscience research 2008
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Human Polyclonal BDNF Primary Antibody for CyTOF, FACS - ABIN4899237
Xapelli, Bernardino, Ferreira, Grade, Silva, Salgado, Cavadas, Grouzmann, Poulsen, Jakobsen, Oliveira, Zimmer, Malva: Interaction between neuropeptide Y (NPY) and brain-derived neurotrophic factor in NPY-mediated neuroprotection against excitotoxicity: a role for microglia. in The European journal of neuroscience 2008
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Human Polyclonal BDNF Primary Antibody for ICC, IF - ABIN409162
Atasoy, Dursun, Gezen-Ak, Metin-Armağan, Öztürk, Yılmazer: Both secreted and the cellular levels of BDNF attenuated due to tau hyperphosphorylation in primary cultures of cortical neurons. in Journal of chemical neuroanatomy 2016
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Human Polyclonal BDNF Primary Antibody for IF (p), IHC (p) - ABIN1387788
Zhao, Li, Wei, Savage, Zhou, Ma: Ketamine administered to pregnant rats in the second trimester causes long-lasting behavioral disorders in offspring. in Neurobiology of disease 2014
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Human Polyclonal BDNF Primary Antibody for EIA, WB - ABIN115983
Hartog, Dittrich, Pieneman, Jansen, Frankl-Vilches, Lessmann, Lilliehook, Goldman, Gahr: Brain-derived neurotrophic factor signaling in the HVC is required for testosterone-induced song of female canaries. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2009
Human Polyclonal BDNF Primary Antibody for EIA, Func - ABIN115986
Miknyoczki, Wan, Chang, Dobrzanski, Ruggeri, Dionne, Buchkovich: The neurotrophin-trk receptor axes are critical for the growth and progression of human prostatic carcinoma and pancreatic ductal adenocarcinoma xenografts in nude mice. in Clinical cancer research : an official journal of the American Association for Cancer Research 2002
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Human Polyclonal BDNF Primary Antibody for EIA, Func - ABIN115985
Wirth, Patz, Wahle: Transcellular induction of neuropeptide Y expression by NT4 and BDNF. in Proceedings of the National Academy of Sciences of the United States of America 2005
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Human Monoclonal BDNF Primary Antibody for ICC, ELISA - ABIN1724944
Yoshida, Ishikawa, Niitsu, Nakazato, Watanabe, Shiraishi, Shiina, Hashimoto, Kanahara, Hasegawa, Enohara, Kimura, Iyo, Hashimoto: Decreased serum levels of mature brain-derived neurotrophic factor (BDNF), but not its precursor proBDNF, in patients with major depressive disorder. in PLoS ONE 2012
Human Monoclonal BDNF Primary Antibody for FACS, ICC - ABIN4283827
Lambert, Carlson, Formichella, Sappington, Ahlem, Calkins: Oral Delivery of a Synthetic Sterol Reduces Axonopathy and Inflammation in a Rodent Model of Glaucoma. in Frontiers in neuroscience 2017
These results show that miR (显示 MLXIP 抗体)-497 inhibits thyroid cancer by suppressing BDNF, suggesting that miR (显示 MLXIP 抗体)-497 is a potential therapeutic target for thyroid cancer.
BDNF enriched in colorectal carcinoma can interact and inhibit UGT2B7 (显示 UGT2B7 抗体) by primarily blocking the positive signals of H3K4Me3 as well as activating H3K27Ac on the promoter region of UGT2B7 (显示 UGT2B7 抗体).
Met carriers for BDNF rs6265 are at higher risk of developing posttraumatic stress disorder (PTSD) and also exhibit more severe PTSD symptoms than Val/Val homozygotes among flood survivors in China.
Val66Met SNP carriers may not exhibit intensity-dependent changes in serum BDNF concentration after exercise in incomplete spinal cord injury.
BDNF Met/Met genotype is associated with increased lifetime history of concussions in active-duty soldiers.
This study shown the interactions between DNA methylation (显示 HELLS 抗体) (CpG5) of the BDNF gene promoter and the tag SNP (rs6265) play important roles in the etiology of Amnestic Mild Cognitive Impairment and its conversion to Alzheimer's Disease.
This study indicates an association between polymorphisms in genes related to the serotonin pathway and positive outcomes in young children with FXS treated with sertraline. The molecular biomarker that was most responsive to the effects of sertraline from the Clinical Global Impression Scale-Improvement perspective was the BDNF genotype
We thus conclude that both metabolically demanding sprint interval exercise and muscle damage inflicting stretch-shortening cycle exercise induced long-lasting decrease in circulating BDNF which may not promote brain health.
Higher peripheral BDNF in autism is concordant with several neurological and psychological theories on the causes and symptoms of this condition, and it contrasts notably with the lower levels of BDNF found in schizophrenia, bipolar disorder, and depression.
These results suggest that elevation of peripheral BDNF promoter methylation might be used as potential epigenetic biomarkers for predicting the conversion from Amnestic Mild Cognitive Impairment to Alzheimer's Disease.
newborn neurons improve social recognition persistence through a BDNF-independent mechanism.
Study shows long-term physical exercise in mice led to a significant increase in the synthesis and release of brain derived neurotrophic factor along with an alteration in the morphology of astrocytes in the dentate gyrus.
Mice exposed to aggressive confrontations exhibited a similar pattern of species-typical aggressive and non-aggressive behaviors on the first and the last session. Repeated aggressive confrontations promoted an increase in plasma corticosterone. Repeated sessions of social instigation or aggressive confrontation did not alter BDNF concentrations at the prefrontal cortex and hippocampus.
High-intensity acute exercise increased total Bdnf mRNA in hippocampus of sedentary mice.
Thus, the expression of BDNF in the hippocampal CA1 (显示 CA1 抗体) region has the potential to improve fear and object location memory in wild type mouse strains when the region and expression levels of BDNF are well controlled.
Study demonstrates the importance of 14,15-EET-mediated production of astrocyte-derived brain derived neurotrophic factor for enhancing viability of astrocytes and protecting neurons from the ischaemic injury and provides insights into the mechanism by which 14,15-EET is involved in neuroprotection.
Orthopedic surgery modulates the expression of neuropeptide Y (显示 NPY 抗体) and BDNF at the spinal and hippocampal levels.
treating BACHD cortical neurons with ApiCCT1 prevented BACHD striatal neuronal atrophy by enhancing release of BDNF that subsequently acts through tyrosine receptor kinase B (TrkB (显示 NTRK2 抗体)) receptor on striatal neurons. Our findings are evidence that TRiC (显示 MARVELD2 抗体) reagent-mediated reductions in mHTT enhanced BDNF delivery to restore the trophic status of BACHD striatal neurons.
BDNF in the lower parts of the auditory system drives auditory fidelity along the entire ascending pathway up to the cortex by increasing inhibitory strength in behaviorally relevant frequency regions.
Results highlight the biological significance of alternative brain-derived neurotrophic factor transcripts and provide evidence that individual isoforms serve distinct molecular and behavioral functions.
One of the modulators of TOR (显示 FRAP1 抗体) is brain-derived neurotrophic factor (BDNF), which activates the TOR (显示 FRAP1 抗体) signaling pathway to promote protein synthesis, synapse strengthening, and the creation of new neural networks.findings demonstrate that TOR (显示 FRAP1 抗体) activation in old animals occurs in the early phase of consolidation, and follows a pattern identical to that of BDNF expression.
These results suggest an involvement of the BDNF/TrkB (显示 NTRK2 抗体) system in the regulation of food intake and energy balance in zebrafish, as in mammals
BDNF-TrkB (显示 NTRK2 抗体) influences the expression level of components of chemokine (显示 CCL1 抗体) signaling including Cxcr4b, and the generation of progenitors of mechanoreceptors, at the level of expression of Atoh1a-Atp2b1a.
Light regulates the expression of the BDNF/TrkB2 (显示 NTRK2 抗体) system in the adult zebrafish retina.
Brain-derived neurotrophic factor (BDNF) induces polarized signaling of small GTPase (显示 RACGAP1 抗体) (Rac1) protein at the onset of Schwann cell myelination through partitioning-defective 3 (Par3 (显示 PARD3 抗体)) protein.
the results demonstrate that bdnf mediates non-cell-autonomous maintenance of position and thereby the identity of differentiated neurons
The present results demonstrate that there is a parallel time-related decline in the expression of BDNF and TrkB (显示 NTRK2 抗体) in zebrafish.
The cloning and analysis of three additional zebrafish (Danio rerio) BDNF gene exons and two associated promoters, is reported. Among them are two exons that generate a novel tripartite mature transcript
Loss of BDNF is a major cause of the developmental abnormalities seen with huntingtin (显示 HTT 抗体) knockdown in zebrafish.
Together these results suggest an important role of BDNF in the maintenance and regeneration of the olfactory system.
BDNF suppresses neuromuscular junction maturation through cAMP-PKA signaling pathway
Findings demonstrate the neurotrophin, BDNF-dependent formation of integrin beta1-based adhesions in the growth cone and reveal how a positive regulator of substrate adhesions can block the negative remodeling and growth inhibitory effects of myelin-associated glycoprotein (显示 MAG 抗体) .
These results indicate that brief sensory stimulation, by initiating nuclear transcription and de novo protein synthesis of BDNF, can facilitate the refinement of response properties in the developing visual system.
In the Xenopus melanotrope, BDNF biosynthesis and processing occur along the secretory granule maturation axis, together with that of POMC (显示 POMC 抗体)-derived alphaMSH (显示 POMC 抗体), and that the light controls the biosynthesis and secretion of BDNF and of POMC (显示 POMC 抗体) end-products.
BDNF released from the neural lobe of the pituitary gland acts as a neurohormone stimulating the secretory activity of the melanotrope cells in the intermediate pituitary lobe.
BDNF influences synaptic connectivity in multiple ways, promoting not only the morphological maturation of axonal arbors but also their stabilization, but also their stabilization.
BDNF, in addition to its neural and hormonal roles, can be released as a neurohormone from the neural pituitary lobe of X. laevis
BDNF induces glial cell proliferation as well as axonal outgrowth and myelination in vivo.
PACAP stimulates the expression of BDNF transcript IV.
Lf upregulated several canonical signaling pathways associated with neurodevelopment and cognition and influenced ~10 genes involved in the brain-derived neurotrophin factor (BDNF) signaling pathway.
Taken together, these data indicate that recurrent tethering stress in sows over 4.5 years results in a loss of neurotrophic support by BDNF, mediated by an overactive neuroendocrine system.
FiO2 used for resuscitation affects matrix metalloproteinases MMP-9 (显示 MMP9 抗体) and MMP-2 (显示 MMP2 抗体), caspase-3 (显示 CASP3 抗体) and BDNF
These observations provided evidence that brain-derived naeurotrophic factor(BDNF) and its receptor (BDNF receptor) secreted by bovine sperm was important in regulation of insulin (显示 INS 抗体) and leptin (显示 LEP 抗体).
Expressed in ganglionic neuron-like tumor cells, which may activate an embryonic pathway involving BDNF.
Study showed that complex relationships exist between BDNF/TrkB (显示 NTRK2 抗体) gene expression and interneuron marker gene expression that appear to be dependent on the presence of testosterone at adolescence
In a monkey model, cortical BDNF and activity regulated cytoskeletal-associated protein ARC (显示 Arc 抗体) expressions are strongly correlated with spontaneous physical activity.
A SNP is present in rhesus macaques and is able to affect BDNF peripheral levels, thus making this primate model a fundamental tool to study gene by environment interactions involving the BDNF gene.
In monkey the decline of the BDNF protein level started earlier in the sensory and motor neocortical areas than in the association neocortical areas.
The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene.
, brain derived neurothrophic factor
, brain derived neurotrophic factor
, anorexia BDNF
, brain-derived neurotrophic factor
, neurotrophic factor