RRP8 抗体
(Ribosomal RNA Processing 8 (RRP8))
Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys- 9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown.
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24 results
RRP8
适用: 人
WB, ELISA, IF, ICC
宿主: 兔
Polyclonal
unconjugated
RRP8
适用: 人, 大鼠, Cow, 马, 兔, 豚鼠, 犬, Saccharomyces cerevisiae
WB
宿主: 兔
Polyclonal
unconjugated
1 image
Aliases for RRP8 抗体
ribosomal RNA processing 8 (RRP8) 抗体ribosomal RNA processing 8, methyltransferase, homolog (yeast) (Rrp8) 抗体
ribosomal RNA processing 8 (Rrp8) 抗体
1500003O22Rik 抗体
2900001K19Rik 抗体
AW538116 抗体
KIAA0409 抗体
RGD1308302 抗体
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