(RRN3 RNA Polymerase I Transcription Factor (RRN3))
Required for efficient transcription initiation by RNA polymerase I. Required for the formation of the competent preinitiation complex (PIC). Dissociates from pol I as a consequence of transcription. In vitro, cannot activate transcription in a subsequent transcription reaction.
Amit, Sela, Keren, Melamed, Muler, Shomron, Izraeli, Ast: "Biased exonization of transposed elements in duplicated genes: A lesson from the TIF-IA gene." in: BMC molecular biology, Vol. 8, pp. 109, (2008) (PubMed).