This gene encodes a member of the R-Ras subfamily of Ras-like small GTPases. The encoded protein associates with the plasma membrane and may function as a signal transducer. This protein may play an important role in activating signal transduction pathways that control cell proliferation. Mutations in this gene are associated with the growth of certain tumors. Pseudogenes of this gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010].
Patmore, Welch, Fulkerson, Wu, Choi, Eaves, Kordich, Collins, Cripe, Ratner: "In vivo regulation of TGF-? by R-Ras2 revealed through loss of the RasGAP protein NF1." in: Cancer research, Vol. 72, Issue 20, pp. 5317-27, (2012) (PubMed).
Aliases for RRAS2 抗体
Ras-related protein R-Ras2 (TVAG_453070) 抗体 Ras-related protein R-Ras2 (Bm1_46660) 抗体 RAS related 2 (RRAS2) 抗体 related RAS viral (r-ras) oncogene 2 (Rras2) 抗体 related RAS viral (r-ras) oncogene homolog 2 (RRAS2) 抗体 RAS related 2 (Rras2) 抗体 2610016H24Rik 抗体 C86394 抗体 TC21 抗体