RNF2 产品
(Ring Finger Protein 2 (RNF2))
Categories
Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity. [provided by RefSeq, Jul 2008].
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Featured RNF2 Categories
RNF2 抗体
High quality antibodies with extensive validation data.
RNF2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
RNF2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RNF2 抗体
Product
Reactivity
Application
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Cat. No.
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Datasheet
Reactivity
Human
Application
WB, ELISA, RNAi
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- (3)
- (6)
Cat. No.
ABIN562662
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
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- (9)
Cat. No.
ABIN519808
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP, ChIP
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- (8)
Cat. No.
ABIN6147029
Quantity
100 μL
Datasheet
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Recommended RNF2 ELISA试剂盒
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Analytical Method
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Cat. No.
ABIN6207349
Quantity
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Recommended RNF2 蛋白
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Cat. No.
ABIN1318329
Quantity
10 μg
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Reactivity
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Source
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Cat. No.
ABIN1318331
Quantity
10 μg
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Reactivity
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Source
Insect Cells
Validations
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Cat. No.
ABIN3094999
Quantity
1 mg
Datasheet
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Latest Publications for our RNF2 Products
: "Polycomb repressor complex 1 promotes gene silencing through H2AK119 mono-ubiquitination in acinar-to-ductal metaplasia and pancreatic cancer cells." in: Oncotarget, Vol. 7, Issue 10, pp. 11424-33, (2016) (PubMed).: "The nucleoporin Nup153 regulates embryonic stem cell pluripotency through gene silencing." in: Genes & development, Vol. 29, Issue 12, pp. 1224-38, (2015) (PubMed).
: "YY1 DNA binding and interaction with YAF2 is essential for Polycomb recruitment." in: Nucleic acids research, Vol. 42, Issue 4, pp. 2208-23, (2014) (PubMed).
: "TRIM37 is a new histone H2A ubiquitin ligase and breast cancer oncoprotein." in: Nature, Vol. 516, Issue 7529, pp. 116-20, (2014) (PubMed).
: "Scmh1 has E3 ubiquitin ligase activity for geminin and histone H2A and regulates geminin stability directly or indirectly via transcriptional repression of Hoxa9 and Hoxb4." in: Molecular and cellular biology, Vol. 33, Issue 4, pp. 644-60, (2013) (PubMed).
: "Proteomic and functional analyses reveal the role of chromatin reader SFMBT1 in regulating epigenetic silencing and the myogenic gene program." in: The Journal of biological chemistry, Vol. 288, Issue 9, pp. 6238-47, (2013) (PubMed).
: "Alu elements in ANRIL non-coding RNA at chromosome 9p21 modulate atherogenic cell functions through trans-regulation of gene networks." in: PLoS genetics, Vol. 9, Issue 7, pp. e1003588, (2013) (PubMed).
: "Bmi1 facilitates primitive endoderm formation by stabilizing Gata6 during early mouse development." in: Genes & development, Vol. 26, Issue 13, pp. 1445-58, (2012) (PubMed).
: "Distinct histone modifications in stem cell lines and tissue lineages from the early mouse embryo." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 24, pp. 10783-90, (2010) (PubMed).
: "Polycomb-group complex 1 acts as an E3 ubiquitin ligase for Geminin to sustain hematopoietic stem cell activity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 30, pp. 10396-401, (2008) (PubMed).
Synonyms and alternative names related to RNF2
ring finger protein 2 (RNF2), ring finger protein 2 (Rnf2), ring finger protein 2 (rnf2), ring finger protein 2 L homeolog (rnf2.L), AI326319, AI450156, AU019207, BAP-1, bap-1, BAP1, bap1, DING, dinG, ding, fa19h05, HIPI3, hipi3, RING1B, Ring1B, ring1b, RING2, ring2, wu:fa19h05, wz4556Protein level used designations for RNF2
- E3 ubiquitin-protein ligase RING2
- HIP2-interacting protein 3
- RING finger protein 1B
- RING finger protein BAP-1
- huntingtin-interacting protein 2-interacting protein 3
- protein DinG
- RING1b
- ring finger protein 1b
- wz4566
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