RNF170 抗体
(Ring Finger Protein 170 (RNF170))
This gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1,4,5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012].
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Latest Publications for our RNF170 抗体
: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).
Aliases for RNF170 抗体
ring finger protein 170 (Rnf170) 抗体ring finger protein 170 (RNF170) 抗体
ring finger protein 170 L homeolog (rnf170.L) 抗体
microRNA 4469 (MIR4469) 抗体
6720407G21Rik 抗体
AI481227 抗体
SNAX1 抗体
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