RNF169 抗体
(Ring Finger Protein 169 (RNF169))
Probable E3 ubiquitin-protein ligase that acts as a negative regulator of double-strand breaks (DSBs) repair following DNA damage. Recruited to DSB repair sites by recognizing and binding ubiquitin catalyzed by RNF168 and competes with TP53BP1 and BRCA1 for association with RNF168-modified chromatin, thereby acting as a negative regulator of DSBs repair. E3 ubiquitin- protein ligase activity is not required for regulation of DSBs repair (By similarity).
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RNF169
适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, Bat, 小鸡, Pig, 非洲爪蟾
WB
宿主: 兔
Polyclonal
unconjugated
1 image
Aliases for RNF169 抗体
ring finger protein 169 (RNF169) 抗体ring finger protein 169 (Rnf169) 抗体
2900057K09Rik 抗体
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