RNF139 抗体
(Ring Finger Protein 139 (RNF139))
The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. [provided by RefSeq, Jul 2008].
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33 results
RNF139
适用: 小鼠
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 555
RNF139
适用: Schizosaccharomyces pombe
WB, ELISA, IHC
宿主: 兔
Polyclonal
unconjugated
RNF139
适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 马
WB
宿主: 兔
Polyclonal
unconjugated
1 image
Latest Publications for our RNF139 抗体
: "A meckelin-filamin A interaction mediates ciliogenesis." in: Human molecular genetics, Vol. 21, Issue 6, pp. 1272-86, (2012) (PubMed).: "The TRC8 ubiquitin ligase is sterol regulated and interacts with lipid and protein biosynthetic pathways." in: Molecular cancer research : MCR, Vol. 8, Issue 1, pp. 93-106, (2010) (PubMed).
: "The sterol-sensing endoplasmic reticulum (ER) membrane protein TRC8 hampers ER to Golgi transport of sterol regulatory element-binding protein-2 (SREBP-2)/SREBP cleavage-activated protein and reduces ..." in: The Journal of biological chemistry, Vol. 284, Issue 42, pp. 28995-9004, (2009) (PubMed).
: "The TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ER." in: The Journal of cell biology, Vol. 186, Issue 5, pp. 685-92, (2009) (PubMed).
: "RING-dependent tumor suppression and G2/M arrest induced by the TRC8 hereditary kidney cancer gene." in: Oncogene, Vol. 26, Issue 16, pp. 2263-71, (2007) (PubMed).
Aliases for RNF139 抗体
ring finger protein 139 (RNF139) 抗体ring finger protein 139 (Rnf139) 抗体
ring finger protein 139 (rnf139) 抗体
ring finger protein 139 S homeolog (rnf139.S) 抗体
4930555P18Rik 抗体
HRCA1 抗体
RCA1 抗体
rnf139 抗体
TRC8 抗体
zgc:175173 抗体
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